Kirkpatrick C H
Department of Medicine, University of Colorado Health Sciences Center, Denver 80206-1210, USA.
Pediatr Infect Dis J. 2001 Feb;20(2):197-206. doi: 10.1097/00006454-200102000-00017.
Chronic mucocutaneous candidiasis should be viewed as a spectrum of disorders in which the patients have persistent and/or recurrent candidiasis of the skin, nails and mucous membranes. Some of the conditions have genetic predispositions. A common immunologic abnormality is failure of the patient's T lymphocytes to produce cytokines that are essential for expression of cell-mediated immunity to Candida. Antifungal drugs are effective in clearing the infections, and treatments that restore cellular immunity have produced long term remissions.
慢性黏膜皮肤念珠菌病应被视为一系列病症，其中患者皮肤、指甲和黏膜存在持续性和/或复发性念珠菌感染。部分病症具有遗传易感性。一种常见的免疫异常是患者的T淋巴细胞无法产生对念珠菌细胞介导免疫表达至关重要的细胞因子。抗真菌药物在清除感染方面有效，恢复细胞免疫的治疗已产生长期缓解效果。
