改良旋转血栓弹性描记术方案联合组织型纤溶酶原激活剂用于检测低纤维蛋白溶解和高纤维蛋白溶解。
Modified Rotational Thromboelastometry Protocol Using Tissue Plasminogen Activator for Detection of Hypofibrinolysis and Hyperfibrinolysis.
机构信息
Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
出版信息
Methods Mol Biol. 2023;2663:763-773. doi: 10.1007/978-1-0716-3175-1_51.
Viscoelastic testing includes thromboelastography (TEG) and thromboelastometry (ROTEM) and is widely used in bleeding patients to detect hypocoagulability and guide transfusion therapy. However, the ability of standard viscoelastic tests to assess fibrinolytic capacity is limited. We here describe a modified ROTEM protocol with addition of tissue plasminogen activator that can be used to identify hypofibrinolysis or hyperfibrinolysis.
黏弹性检测包括血栓弹力描记术（TEG）和血栓弹力图（ROTEM），广泛用于出血患者以检测低凝状态并指导输血治疗。然而，标准的黏弹性检测对评估纤维蛋白溶解能力的能力有限。我们在此描述了一种改良的 ROTEM 方案，加入组织型纤溶酶原激活物，可用于识别低纤维蛋白溶解或高纤维蛋白溶解。
Zotero 插件