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Lawsonia intracellularis T3SS effector LI0758, an Rce1 ortholog, activates MAPK and NF-κB signaling in mammalian cells.胞内劳森菌T3SS效应蛋白LI0758（Rce1的直系同源物）可激活哺乳动物细胞中的MAPK和NF-κB信号通路。
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Characterisation of autophagy disruption in the ileum of pigs infected with Lawsonia intracellularis.空肠内细胞劳森菌感染的自噬作用破坏的特征。
Vet Res Commun. 2022 Jun;46(2):585-592. doi: 10.1007/s11259-021-09847-7. Epub 2021 Oct 20.
2
Probiotics mediated gut microbiota diversity shifts are associated with reduction in histopathology and shedding of Lawsonia intracellularis.益生菌介导的肠道微生物群多样性变化与细胞内劳森菌组织病理学的减轻和脱落有关。
Anim Microbiome. 2021 Mar 4;3(1):22. doi: 10.1186/s42523-021-00084-6.
3
Bacillus pumilus probiotic feed supplementation mitigates Lawsonia intracellularis shedding and lesions.短小芽孢杆菌益生菌饲料补充可减轻肠型密螺旋体的脱落和病变。
Vet Res. 2019 Oct 22;50(1):85. doi: 10.1186/s13567-019-0696-1.
4
LI1035, a putative effector secreted by Lawsonia intracellularis, targets the MAPK pathway and regulates actin organizationin yeast and mammalian cells.LI1035，一种由细胞内罗森尼亚菌分泌的假定效应物，靶向 MAPK 通路并调节酵母和哺乳动物细胞中的肌动蛋白组织。
Vet Microbiol. 2019 Aug;235:127-135. doi: 10.1016/j.vetmic.2019.06.009. Epub 2019 Jun 11.
5
A Cell Proliferation and Inflammatory Signature Is Induced by Lawsonia intracellularis Infection in Swine.猪体内 Lawsonia intracellularis 感染诱导细胞增殖和炎症特征。
mBio. 2019 Jan 29;10(1):e01605-18. doi: 10.1128/mBio.01605-18.
6
: Revisiting the Disease Ecology and Control of This Fastidious Pathogen in Pigs.重新审视这种挑剔性猪病原体的疾病生态学及防控措施
Front Vet Sci. 2018 Aug 9;5:181. doi: 10.3389/fvets.2018.00181. eCollection 2018.
7
Lawsonia intracellularis exploits β-catenin/Wnt and Notch signalling pathways during infection of intestinal crypt to alter cell homeostasis and promote cell proliferation.胞内劳森菌在感染肠道隐窝期间利用β-连环蛋白/ Wnt和Notch信号通路来改变细胞稳态并促进细胞增殖。
PLoS One. 2017 Mar 21;12(3):e0173782. doi: 10.1371/journal.pone.0173782. eCollection 2017.
8
Comparative transcriptional analysis of homologous pathogenic and non-pathogenic Lawsonia intracellularis isolates in infected porcine cells.同源致病性和非致病性内罗毕胞内体分离株在感染猪细胞中的比较转录分析。
PLoS One. 2012;7(10):e46708. doi: 10.1371/journal.pone.0046708. Epub 2012 Oct 3.
9
Evidence of host adaptation in Lawsonia intracellularis infections. Lawsonia intracellularis 感染中宿主适应性的证据。
Vet Res. 2012 Jun 20;43(1):53. doi: 10.1186/1297-9716-43-53.
10
Identifying obstacles to reducing the use of antibiotics to control porcine proliferative enteropathy.确定减少使用抗生素控制猪增生性肠炎的障碍。
Aust Vet J. 2009 Jan-Feb;87(1):33-4. doi: 10.1111/j.1751-0813.2008.00372.x.

Editorial: : a problem well understood is a problem half solved.

作者信息

Karuppannan Anbu Kumar

机构信息

Department of Veterinary Microbiology, Bioinformatics Centre, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai, India.

出版信息

Front Vet Sci. 2023 May 2;10:1203702. doi: 10.3389/fvets.2023.1203702. eCollection 2023.

DOI:10.3389/fvets.2023.1203702
PMID:37205227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10185883/
Abstract
摘要