Gibbs J L, Wharton G A, Williams G J
Eur Heart J. 1986 Apr;7(4):353-6. doi: 10.1093/oxfordjournals.eurheartj.a062073.
In order to define ranges of normal velocities for the Carpentier-Edwards xenograft, 38 mitral, 24 aortic and 9 tricuspid prostheses were studied with pulsed or continuous wave Doppler at a mean interval of 38 months following surgery. All patients had clinically normal prosthetic valve function and no clinical or radiographic signs of heart failure. Mean peak velocity across aortic prostheses was 244 cm s-1 (SD 48). There was weak correlation (r = 0.54, P less than 0.01) between peak velocity and time since valve implantation, but no significant difference in peak velocity across valves of different size. In the mitral position, mean peak velocity was 164 cm s-1 (SD 24) and mean pressure half time 90 ms (SD 23). There was again no significant difference between valves of different size. There was a weak correlation between pressure half time and time since implantation (r = 0.44, P less than 0.01), but there was no relationship between the latter and peak velocity. In the tricuspid position, mean peak velocity was 150 cm s-1 (SD 12) and mean pressure half time 163 ms (SD 50). The Doppler indices of obstruction to blood flow for prostheses in the mitral and aortic positions showed a significant increase with time after implantation.
为了确定卡彭蒂埃 - 爱德华兹异种移植瓣膜的正常流速范围，对38个二尖瓣、24个主动脉瓣和9个三尖瓣人工瓣膜进行了研究，这些研究在术后平均38个月时采用脉冲或连续波多普勒进行。所有患者的人工瓣膜功能在临床上均正常，且无心力衰竭的临床或影像学征象。主动脉人工瓣膜的平均峰值流速为244 cm/s（标准差48）。峰值流速与瓣膜植入后的时间之间存在弱相关性（r = 0.54，P < 0.01），但不同尺寸瓣膜的峰值流速无显著差异。在二尖瓣位置，平均峰值流速为164 cm/s（标准差24），平均压力减半时间为90 ms（标准差23）。不同尺寸的瓣膜之间同样没有显著差异。压力减半时间与植入后的时间之间存在弱相关性（r = 0.44，P < 0.01），但后者与峰值流速之间没有关系。在三尖瓣位置，平均峰值流速为150 cm/s（标准差12），平均压力减半时间为163 ms（标准差50）。二尖瓣和主动脉瓣位置人工瓣膜血流受阻的多普勒指标在植入后随时间显著增加。
