Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, Sichuan, China.
Front Public Health. 2023 May 4;11:1132199. doi: 10.3389/fpubh.2023.1132199. eCollection 2023.
Lead is a toxic element of the environment that leads to major complications once it enters the blood stream, affecting multiple organs and systems of the body.
We present a case of a 6-month-old female infant diagnosed with lead poisoning after presenting for routine child health care. The child's mother denied that the infant had a history of exposure to lead-containing substances. After a month of calcium supplementation, the patient's blood lead level remained elevated. We then tested the blood lead level of the mother and father. The results showed that the blood lead level of the mother was 77.0 μg/L and that of the father was 36.9 μg/L. The high blood lead level of the mother attracted our attention. We found that the mother had been using an external traditional Chinese medicine, Hu Wang Fen, which contains lead. After the mother's discontinuation of use of the traditional medicine, the child was treated with symptomatic treatment and chelation therapy. Subsequently, the patient's blood lead level decreased significantly.
Lead toxicity can be a life-threatening problem because of its potential for severe complications. In children, there is no safe blood lead level, and the toxic effects of lead can be prevented by the awareness and avoidance of traditional Chinese medicines that may contain lead.
Even though the diagnosis of lead poisoning remains difficult in children, it must be taken into consideration by the clinician when treating a child using traditional Chinese medicines.
铅是环境中的一种有毒元素,一旦进入血液,会导致多种并发症,影响身体的多个器官和系统。
我们报告了一例 6 个月大的女性婴儿,因常规儿童保健就诊而被诊断为铅中毒。患儿母亲否认婴儿有接触含铅物质的病史。在补钙治疗 1 个月后,患儿的血铅水平仍居高不下。我们随后检测了母亲和父亲的血铅水平。结果显示,母亲的血铅水平为 77.0μg/L,父亲的血铅水平为 36.9μg/L。母亲的高血铅水平引起了我们的注意。我们发现母亲一直在使用一种含有铅的外用中药——虎黄粉。在母亲停止使用这种中药后,对患儿进行了对症治疗和螯合治疗。随后,患儿的血铅水平显著下降。
铅毒性可能是一个危及生命的问题,因为它可能会导致严重的并发症。对于儿童,没有安全的血铅水平,通过提高对可能含有铅的中药的认识并避免使用这些中药,可以预防铅的毒性作用。
尽管儿童铅中毒的诊断仍然具有挑战性,但在使用中药治疗儿童时,临床医生必须考虑到这一点。