Rayamajhi Sumugdha, Sharma Shailendra, Regmi Subash, Anwar Farah M, Gandhi Hardik
Internal Medicine, Michigan State University College of Human Medicine, East Lansing, USA.
Nephrology, Sparrow Health System, Lansing, USA.
Cureus. 2023 Apr 19;15(4):e37817. doi: 10.7759/cureus.37817. eCollection 2023 Apr.
Hypertensive emergency is a common cause of emergency room (ER) visits. Scleroderma renal crisis (SRC) is one of the rare causes of hypertensive emergency. SRC is a life-threatening condition that presents with acute onset severe hypertension accompanied by retinopathy, encephalopathy, and rapidly worsening renal function. We present a case of hypertensive emergency and renal failure with positive anti-Scl 70 and RNA polymerase III which is characteristic of SRC. Despite appropriate supportive care and timely treatment with angiotensin-converting enzyme inhibitors, the patient progressed to end-stage kidney disease.
高血压急症是急诊室（ER）就诊的常见原因。硬皮病肾危象（SRC）是高血压急症的罕见原因之一。SRC是一种危及生命的疾病，表现为急性起病的严重高血压，并伴有视网膜病变、脑病和迅速恶化的肾功能。我们报告一例高血压急症和肾衰竭患者，其抗Scl 70和RNA聚合酶III呈阳性，这是SRC的特征。尽管给予了适当的支持治疗并及时使用了血管紧张素转换酶抑制剂，但患者仍进展为终末期肾病。
