Dotis John, Kondou Antonia, Karava Vasiliki, Sotiriou Georgia, Papadopoulou Athina, Zarras Charalampos, Michailidou Chrysi, Vagdatli Eleni, Printza Nikoleta
First Department of Pediatrics, Medical Faculty, School of Health Sciences, Aristotle University of Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
Department of Microbiology, Medical Faculty, School of Health Sciences, Aristotle University of Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
Pediatr Rep. 2023 Apr 25;15(2):293-300. doi: 10.3390/pediatric15020025.
is a Gram-negative bacillus that can rarely cause infections in humans. We recently treated a case of peritonitis due to in a peritoneal dialysis (PD) pediatric patient, and we systematically reviewed all the relevant reported cases in the literature. We searched the PubMed and Scopus databases, and we reviewed 13 such cases (2 children, 11 adults) that were reported, including our patient. The mean (±SE) age was 53.2 ± 22.5 years, with a male-to-female ratio of approximately 1:1.6. Their mean vintage period on PD prior to peritonitis was 37.5 ± 25.3 months. The VITEK card was the identification diagnostic tool in most cases (63%). The antimicrobial agent that was most frequently used was ceftazidime, which was implemented in 50% of cases as initial therapy, either as a monotherapy or combination therapy; in only two patients (15.3%) was the Tenkhoff catheter removed. The median duration of treatment was 18 days (range of 10-21 days), and all 13 patients that were reviewed were healed. Physicians should be aware that is noted to rarely cause peritonitis in PD patients; however, this pathogen seems to be sensitive to most antimicrobial agents and can result in a favorable outcome with the selection of appropriate treatment.
是一种革兰氏阴性杆菌，很少能引起人类感染。我们最近治疗了一名腹膜透析（PD）儿科患者因[未提及具体杆菌名称]导致的腹膜炎病例，并系统回顾了文献中所有相关的报告病例。我们检索了PubMed和Scopus数据库，回顾了包括我们的患者在内已报告的13例此类病例（2名儿童，11名成人）。平均（±标准误）年龄为53.2±22.5岁，男女比例约为1:1.6。他们在腹膜炎发生前进行PD的平均透析时间为37.5±25.3个月。在大多数病例（63%）中，VITEK卡是鉴定诊断工具。最常用的抗菌药物是头孢他啶，50%的病例将其作为初始治疗药物，单独使用或联合使用；只有两名患者（15.3%）拔除了Tenkhoff导管。治疗的中位持续时间为18天（范围为10 - 21天），所有接受回顾的13名患者均已治愈。医生应意识到[未提及具体杆菌名称]在PD患者中很少引起腹膜炎；然而，这种病原体似乎对大多数抗菌药物敏感，通过选择合适的治疗方法可取得良好的治疗效果。
