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变应原免疫学家的鼻窦炎手术治疗。

Surgical management of rhinosinusitis for the allergist-immunologist.

机构信息

Dartmouth Hitchcock Medical Center, Section of Otolaryngology Head and Neck Surgery, Lebanon, New Hampshire.

Dartmouth Hitchcock Medical Center, Section of Otolaryngology Head and Neck Surgery, Lebanon, New Hampshire.

出版信息

Ann Allergy Asthma Immunol. 2023 Sep;131(3):311-316. doi: 10.1016/j.anai.2023.05.015. Epub 2023 May 21.

Abstract

Chronic rhinosinusitis (CRS) is a common chronic inflammatory disease characterized by inflammation of the sinus, with or without nasal passage inflammation, occurring for more than 12 weeks at a time. CRS has historically been classified in 2 categories: CRS without nasal polyps or CRS with nasal polyps (25%-30% of cases). The mainstay of treatment for CRS with or without nasal polyps is medical management, and options may include a combination of saline irrigation, nasal steroids, allergy medications, antibiotics, oral steroids, and treatment with targeted monoclonal antibodies. Unfortunately, up to 60% of patents report symptoms refractory to maximal medical therapy. As such, a combined approach of surgery and medical therapy may be offered. Endoscopic sinus surgery for CRS is approached in a stepwise fashion, ranging from the simplest technique, such as polyp removal, to more expanded approaches that open the paranasal sinuses and allow gravity-dependent drainage. This review article provides a review and in-depth explanation of various surgical approaches for CRS, including the indications, techniques, and respective outcomes for each one.

摘要

慢性鼻-鼻窦炎(CRS)是一种常见的慢性炎症性疾病,其特征为鼻窦炎症,伴有或不伴有鼻腔通道炎症,每次发作持续超过 12 周。CRS 既往分为 2 类:无鼻息肉的 CRS 或伴鼻息肉的 CRS(占病例的 25%-30%)。有或无鼻息肉的 CRS 的主要治疗方法是药物治疗,选择可能包括盐水冲洗、鼻腔类固醇、过敏药物、抗生素、口服类固醇和靶向单克隆抗体治疗。不幸的是,多达 60%的患者报告对最大程度的药物治疗有反应。因此,可以采用手术和药物治疗相结合的方法。CRS 的内镜鼻窦手术采用逐步的方法,从最简单的技术(如息肉切除术)到更广泛的技术,这些技术打开鼻窦并允许重力依赖性引流。本文综述了 CRS 的各种手术方法,包括适应证、技术和每种方法的相应结果。

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