Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Department of Medical Microbiology, Eurofins-PAMM, Veldhoven, The Netherlands.
Epidemiol Infect. 2023 May 24;151:e95. doi: 10.1017/S0950268823000808.
Toxoplasmosis caused by the protozoan parasite occurs worldwide. Infections range from asymptomatic to life-threatening. infection is acquired either via bradyzoites in meat or via oocysts in the environment, but the relative importance of these path ways and the different sources remains unclear. In this study, possible risk factors for toxoplasmosis in the Netherlands were investigated. A case-control study was conducted including persons with recent infection and individuals with a negative test result for IgM and IgG for between July 2016 and April 2021. A total of 48 cases and 50 controls completed the questionnaire. Food history and environmental exposure were compared using logistic regression. Consumption of different meats was found to be associated with recent infection. In the multivariable model, adjusted for age, gender, and pregnancy, consumption of large game meat (adjusted odds ratio (aOR) 8.2, 95% confidence interval 1.6-41.9) and sometimes (aOR 4.1, 1.1-15.3) or never (aOR 15.9, 2.2-115.5) washing hands before food preparation remained. These results emphasize the value of the advice to be careful with the consumption of raw and undercooked meat. Good hand hygiene could also be promoted in the prevention of infection.
弓形虫病是由原生动物寄生虫引起的，广泛存在于世界各地。感染范围从无症状到危及生命。感染是通过肉中的缓殖子或环境中的卵囊获得的，但这些途径的相对重要性和不同来源仍不清楚。在这项研究中，研究人员调查了荷兰弓形虫病的可能危险因素。一项病例对照研究包括 2016 年 7 月至 2021 年 4 月期间最近感染的人和 IgM 和 IgG 检测结果均为阴性的个体。共有 48 例病例和 50 例对照完成了问卷调查。使用逻辑回归比较了饮食史和环境暴露情况。研究发现，食用不同肉类与近期感染有关。在多变量模型中，调整了年龄、性别和妊娠因素后，食用大型野味（调整后的优势比[aOR] 8.2，95%置信区间 1.6-41.9）和有时（aOR 4.1，1.1-15.3）或从不（aOR 15.9，2.2-115.5）在准备食物前洗手仍与近期感染相关。这些结果强调了注意食用生肉和未煮熟的肉的重要性。在预防弓形虫感染方面，还可以提倡良好的手部卫生。
