Emran Baraa, Arafat Bahaa, Salous Ahmed, Dibas Mohammed, Kharraz Lubna, Belkebir Souad, Damiri Basma
Medicine and Health Sciences, Department of Medicine, An-Najah National University, Nablus, Palestine.
Medicine and Health Sciences, Department of Biomedical Sciences, An-Najah National University, Nablus, Palestine.
Sci Rep. 2025 Mar 21;15(1):9856. doi: 10.1038/s41598-025-90970-9.
A cross-sectional study was conducted in 2024 to study the seroprevalence of Toxoplasma gondii (T. gondii) and male testosterone levels in Palestinian butchers in the West Bank. Sera were collected from 156 butchers and tested for anti-T. gondii-IgG and IgM using commercial immune assay and testosterone tests. Univariate and bivariate analyses were used to calculate crude and adjusted odds ratios. The seroprevalences were 62.8% for anti-T-gondii-IgG, 7.1% for anti-T-gondii-IgM, and 7.1% for both IgG and IgM. T. gondii-IgG seropositive individuals had a median testosterone level of 351 ng/dL, significantly lower than the 428.5 ng/dL observed in T. gondii-IgG seronegative participants (p = 0.017). T. gondii-IgG seropositivity was associated with raw meat consumption, exposure to soil, age, and years of practice with adjusted odd ratios of 3.85, 3.32, 1.10, and 1.27, respectively. However, low testosterone level was not significantly associated with T. gondii seropositivity (p = 0.07). This finding suggests that additional research is needed to understand the relationship between Toxoplasma infection and testosterone levels.
2024年开展了一项横断面研究，以研究约旦河西岸巴勒斯坦屠夫中弓形虫的血清流行率和男性睾酮水平。从156名屠夫中采集血清，使用商业免疫分析法检测抗弓形虫IgG和IgM以及进行睾酮检测。采用单变量和双变量分析来计算粗比值比和调整后的比值比。抗弓形虫IgG的血清流行率为62.8%，抗弓形虫IgM为7.1%，IgG和IgM均为阳性的为7.1%。弓形虫IgG血清阳性个体的睾酮水平中位数为351 ng/dL，显著低于弓形虫IgG血清阴性参与者中观察到的428.5 ng/dL（p = 0.017）。弓形虫IgG血清阳性与食用生肉、接触土壤、年龄和从业年限相关，调整后的比值比分别为3.85、3.32、1.10和1.27。然而，低睾酮水平与弓形虫血清阳性无显著关联（p = 0.07）。这一发现表明，需要进一步研究以了解弓形虫感染与睾酮水平之间的关系。
