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解锁微小的巨头:牙科应用中量子点纳米技术的全景视角。

Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications.

作者信息

Alluhaidan Tasneem, Garcia Isadora Martini, Alexis Meghan, Qaw Masoumah, Collares Fabrício Mezzomo, Williams Mary Ann, Melo Mary Anne S

机构信息

Dental Biomedical Sciences Ph.D. Program, University of Maryland School of Dentistry, Baltimore, MD, United States.

Department of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

Front Dent Med. 2025 Mar 4;6:1503057. doi: 10.3389/fdmed.2025.1503057. eCollection 2025.

Abstract

Quantum dots (QDs) nanotechnology has gained significant attention in dentistry due to its unique properties, such as fluorescence, antimicrobial activity, and drug delivery potential. This review aims to identify the dental applications most actively incorporating QD technology and to examine the distinctive properties of QDs within Dentistry. Employing the Arksey and O'Malley five-stage framework, a systematic search was conducted across PubMed, EMBASE, and Scopus databases for English-language publications on QDs in dentistry. Scientific contributions were evaluated by analyzing publication volume, research trends, patents, and key areas of investigation. Of the 1,034 studies initially identified, 71 were fully screened, with 22 meeting the criteria for data extraction. Results showed that antimicrobial properties and bone regeneration are the primary focus areas for QDs in dental materials. Stock solutions and resin composites are the most common materials developed, with the studies primarily targeting ofenhancing antimicrobial capabilities and osteogenesis enhancement. Over the last decade, QDs have demonstrated potential in enhancing drug delivery, antimicrobial efficacy, and optical performance in dental materials. Despite their growing prominence, the clinical translation of QD-based technologies remains limited due to a lack of long-term studies.

摘要

量子点(QDs)纳米技术因其独特性质,如荧光、抗菌活性和药物递送潜力,在牙科领域受到了广泛关注。本综述旨在确定最积极采用量子点技术的牙科应用,并研究量子点在牙科领域的独特性质。采用阿克斯赛和奥马利的五阶段框架,在PubMed、EMBASE和Scopus数据库中对牙科领域有关量子点的英文出版物进行了系统检索。通过分析出版物数量、研究趋势专利和主要研究领域来评估科学贡献。在最初确定的1034项研究中,71项进行了全面筛选,其中22项符合数据提取标准。结果表明,抗菌性能和骨再生是牙科材料中量子点的主要研究重点。储备溶液和树脂复合材料是最常见的开发材料,这些研究主要目标是提高抗菌能力和成骨能力。在过去十年中,量子点已显示出在增强牙科材料的药物递送、抗菌效果和光学性能方面的潜力。尽管其重要性日益凸显,但由于缺乏长期研究,基于量子点的技术在临床应用方面仍然有限。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6215/11913709/e8052f97bd83/fdmed-06-1503057-g001.jpg

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