Reina Carlos, Roa Pablo, Garcés Anthony, Valencia Andrés, Torres Miyerlandi, Concha-Eastman Alberto
Secretaría de Salud Pública Cali Colombia Secretaría de Salud Pública, Cali, Colombia.
Rev Panam Salud Publica. 2023 May 22;47:e76. doi: 10.26633/RPSP.2023.76. eCollection 2023.
To describe the variation in COVID-19 mortality among residents of Cali, Colombia, in the second wave of the pandemic, before vaccines, and in the fourth wave, with vaccination roll-out in process, taking into account variables of sex, age group, comorbidities, and interval between onset of symptoms and death, and to estimate the number of deaths averted by vaccination.
A cross-sectional study of second wave and fourth wave deaths and vaccination coverage. The frequencies of attributes of deceased population in the two waves were compared, including comorbidities. Machado's method was used to calculate an estimate of the number of deaths averted in the fourth wave.
There were 1 133 deaths in the second wave and 754 deaths in the fourth wave. It was calculated that approximately 3 763 deaths were averted in the fourth wave in Cali in the context of vaccination roll-out.
The decline in COVID-19-associated mortality observed supports the continuation of the vaccination program. Given the lack of data to explain other possible reasons for this decline, such as on the severity of novel viral variants, the limitations of the study are discussed.
描述在哥伦比亚卡利市居民中，在大流行的第二波（疫苗接种前）和第四波（疫苗接种正在推进）期间，新冠病毒疾病（COVID-19）死亡率的变化情况，同时考虑性别、年龄组、合并症以及症状出现至死亡的时间间隔等变量，并估计疫苗接种避免的死亡人数。
对第二波和第四波死亡情况及疫苗接种覆盖率进行横断面研究。比较了两波死亡人群的属性频率，包括合并症。采用马查多方法计算第四波中避免的死亡人数估计值。
第二波有1133例死亡，第四波有754例死亡。经计算，在卡利市疫苗接种推进的背景下，第四波大约避免了3763例死亡。
观察到的与COVID-19相关的死亡率下降支持继续推行疫苗接种计划。鉴于缺乏数据来解释这种下降的其他可能原因，如新型病毒变体的严重性，对该研究的局限性进行了讨论。
