• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

体外膜肺氧合期间的机械通气:最佳实践。

Mechanical Ventilation during ECMO: Best Practices.

机构信息

Division of Pediatric Critical Care, Duke Children's Hospital, Durham, North Carolina.

出版信息

Respir Care. 2023 Jun;68(6):838-845. doi: 10.4187/respcare.10908.

DOI:10.4187/respcare.10908
PMID:37225656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10208991/
Abstract

Adults and children who require extracorporeal membrane oxygenation for respiratory failure remain at risk for ongoing lung injury if ventilator management is not optimized. This review serves as a guide to assist the bedside clinician in ventilator titration for patients on extracorporeal membrane oxygenation, with a focus on lung-protective strategies. Existing data and guidelines for extracorporeal membrane oxygenation ventilator management are reviewed, including non-conventional ventilation modes and adjunct therapies.

摘要

对于因呼吸衰竭而需要体外膜肺氧合的成人和儿童,如果呼吸机管理未得到优化,他们仍将面临持续肺损伤的风险。本综述旨在为床边临床医生提供指导,帮助他们对接受体外膜肺氧合的患者进行呼吸机滴定,重点是肺保护策略。本文回顾了现有的体外膜肺氧合呼吸机管理数据和指南,包括非常规通气模式和辅助治疗。

相似文献

1
Mechanical Ventilation during ECMO: Best Practices.体外膜肺氧合期间的机械通气:最佳实践。
Respir Care. 2023 Jun;68(6):838-845. doi: 10.4187/respcare.10908.
2
Mechanical Ventilation in Children on Venovenous ECMO.儿童静脉-静脉体外膜肺氧合时的机械通气。
Respir Care. 2020 Mar;65(3):271-280. doi: 10.4187/respcare.07214. Epub 2020 Jan 28.
3
Invasive mechanical ventilation in patients with acute respiratory distress syndrome receiving extracorporeal support: a narrative review of strategies to mitigate lung injury.体外膜肺氧合支持下急性呼吸窘迫综合征患者的有创机械通气:减轻肺损伤策略的叙述性综述。
Anaesthesia. 2022 Oct;77(10):1137-1151. doi: 10.1111/anae.15806. Epub 2022 Jul 21.
4
Ultra-Protective Ventilation Reduces Biotrauma in Patients on Venovenous Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome.体外膜肺氧合治疗严重急性呼吸窘迫综合征患者的超保护性通气减少生物创伤。
Crit Care Med. 2019 Nov;47(11):1505-1512. doi: 10.1097/CCM.0000000000003894.
5
Mechanical ventilation in patients subjected to extracorporeal membrane oxygenation (ECMO).体外膜肺氧合(ECMO)患者的机械通气。
Med Intensiva. 2017 Nov;41(8):491-496. doi: 10.1016/j.medin.2016.12.007. Epub 2017 Feb 8.
6
Effect of Driving Pressure Change During Extracorporeal Membrane Oxygenation in Adults With Acute Respiratory Distress Syndrome: A Randomized Crossover Physiologic Study.体外膜肺氧合期间成人急性呼吸窘迫综合征驱动压变化的影响:一项随机交叉生理研究。
Crit Care Med. 2020 Dec;48(12):1771-1778. doi: 10.1097/CCM.0000000000004637.
7
Bleomycin-induced lung injury treated with venovenous extracorporeal membrane oxygenation (ECMO) and ultra-protective ventilator settings.采用静脉-静脉体外膜肺氧合(ECMO)和超保护性通气设置治疗博来霉素诱导的肺损伤。
BMJ Case Rep. 2020 Nov 23;13(11):e236474. doi: 10.1136/bcr-2020-236474.
8
Effect of positive end-expiratory pressure on lung injury and haemodynamics during experimental acute respiratory distress syndrome treated with extracorporeal membrane oxygenation and near-apnoeic ventilation.体外膜肺氧合和近窒息通气治疗实验性急性呼吸窘迫综合征时呼气末正压对肺损伤和血液动力学的影响。
Br J Anaesth. 2021 Nov;127(5):807-814. doi: 10.1016/j.bja.2021.07.031. Epub 2021 Sep 8.
9
Extracorporeal Membrane Oxygenation (ECMO) for Lung Injury in Severe Acute Respiratory Distress Syndrome (ARDS): Review of the Literature.体外膜肺氧合(ECMO)用于严重急性呼吸窘迫综合征(ARDS)中的肺损伤:文献综述
Clin Nurs Res. 2017 Dec;26(6):747-762. doi: 10.1177/1054773816677808. Epub 2016 Nov 11.
10
Rest ventilator management in children on veno-venous extracorporeal membrane oxygenation.在接受静脉-静脉体外膜肺氧合的儿童中进行呼吸机管理的研究
Int J Artif Organs. 2022 Feb;45(2):174-180. doi: 10.1177/0391398821999386. Epub 2021 Mar 15.

引用本文的文献

1
[Special aspects of patients with va-ECMO on the way to organ donation].[接受体外膜肺氧合(VA-ECMO)治疗的患者在器官捐献过程中的特殊情况]
Anaesthesiologie. 2025 Jul;74(7):453-459. doi: 10.1007/s00101-025-01550-5.
2
Navigating Heart-Lung Interactions in Mechanical Ventilation: Pathophysiology, Diagnosis, and Advanced Management Strategies in Acute Respiratory Distress Syndrome and Beyond.机械通气中的心-肺相互作用:急性呼吸窘迫综合征及其他情况下的病理生理学、诊断和高级管理策略
J Clin Med. 2024 Dec 20;13(24):7788. doi: 10.3390/jcm13247788.
3
Extracorporeal membrane oxygenation vs cardiopulmonary bypass in lung transplantation: an updated meta-analysis.肺移植中体外膜肺氧合与体外循环的比较:一项更新的荟萃分析。
Gen Thorac Cardiovasc Surg. 2025 Mar;73(3):137-146. doi: 10.1007/s11748-024-02114-x. Epub 2024 Dec 21.

本文引用的文献

1
Ultra-lung-protective ventilation and biotrauma in severe ARDS patients on veno-venous extracorporeal membrane oxygenation: a randomized controlled study.在接受静脉-静脉体外膜肺氧合的严重急性呼吸窘迫综合征患者中,超保护性通气和生物创伤:一项随机对照研究。
Crit Care. 2022 Dec 12;26(1):383. doi: 10.1186/s13054-022-04272-x.
2
The role of acute hypercapnia on mortality and short-term physiology in patients mechanically ventilated for ARDS: a systematic review and meta-analysis.急性高碳酸血症对急性呼吸窘迫综合征机械通气患者死亡率和短期生理学的影响:系统评价和荟萃分析。
Intensive Care Med. 2022 May;48(5):517-534. doi: 10.1007/s00134-022-06640-1. Epub 2022 Mar 16.
3
Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis.动脉高氧血症与危重症儿童结局的关联:系统评价和荟萃分析。
JAMA Netw Open. 2022 Jan 4;5(1):e2142105. doi: 10.1001/jamanetworkopen.2021.42105.
4
Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis.俯卧位通气在急性呼吸窘迫综合征行静脉-静脉体外膜肺氧合治疗中的应用:系统评价和荟萃分析。
Crit Care. 2021 Aug 12;25(1):292. doi: 10.1186/s13054-021-03723-1.
5
Patient-Self Inflicted Lung Injury: A Practical Review.患者自身造成的肺损伤:实用综述
J Clin Med. 2021 Jun 21;10(12):2738. doi: 10.3390/jcm10122738.
6
Oxygen Toxicity in Critically Ill Adults.危重症成人的氧中毒。
Am J Respir Crit Care Med. 2021 Sep 15;204(6):632-641. doi: 10.1164/rccm.202102-0417CI.
7
Management of Adult Patients Supported with Venovenous Extracorporeal Membrane Oxygenation (VV ECMO): Guideline from the Extracorporeal Life Support Organization (ELSO).成人患者静脉-静脉体外膜肺氧合(VV ECMO)支持管理:体外生命支持组织(ELSO)指南。
ASAIO J. 2021 Jun 1;67(6):601-610. doi: 10.1097/MAT.0000000000001432.
8
Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis.COVID-19 和非 COVID-19 导致的急性呼吸窘迫综合征中皮质类固醇的使用:一项系统评价和荟萃分析。
Intensive Care Med. 2021 May;47(5):521-537. doi: 10.1007/s00134-021-06394-2. Epub 2021 Apr 19.
9
The Nature of Recruitment and De-Recruitment and Its Implications for Management of ARDS.招募和去招募的性质及其对 ARDS 管理的意义。
Respir Care. 2021 Mar;66(3):510-530. doi: 10.4187/respcare.08280. Epub 2020 Oct 13.
10
Effect of Driving Pressure Change During Extracorporeal Membrane Oxygenation in Adults With Acute Respiratory Distress Syndrome: A Randomized Crossover Physiologic Study.体外膜肺氧合期间成人急性呼吸窘迫综合征驱动压变化的影响:一项随机交叉生理研究。
Crit Care Med. 2020 Dec;48(12):1771-1778. doi: 10.1097/CCM.0000000000004637.