Adhikari Yuvraj, Marasini Anupama, Adhikari Nawaraj, Paneru Laxman D, Upadhaya Regmi Binit, Raut Manita
Nepalese Army Institute of Health Sciences.
Upendra Devkota Memorial National Institute of Neurological and Allied Sciences, Kathmandu.
Ann Med Surg (Lond). 2023 Apr 5;85(5):1940-1943. doi: 10.1097/MS9.0000000000000456. eCollection 2023 May.
Oncocytic/Hurthle cell neoplasm is a rare form of thyroid malignancies, derived from follicular epithelium, presenting with a wide variety having either presenting with features of thyrotoxicosis or no any associated symptoms.
The authors present a case of a 49-year-old female with a known case of chronic obstructive pulmonary disease and hypertension who presented to our hospital with anterior neck swelling for 4 months that has gradually increased over the time. Physical examination, laboratory test, various radiological imaging, and cytological study led to the diagnosis of Hurthle cell neoplasm. With prompt diagnosis, she was admitted and surgery was done that include right hemithyroidectomy. Though it is a rare type of thyroid malignancy, early diagnosis and proper treatment has shown a very good prognosis.
Hurthle cell carcinoma initially presents with a single, painless palpable mass in the thyroid with pressure symptoms in advanced cases including dysphagia, dyspnea, and hoarseness. Pain, rapid growth, or significant compressive symptoms are suggestive of an invasive one.
This case highlights on rarity of disease, presentation, and availability of treatment modality.
嗜酸细胞/许特莱细胞肿瘤是一种罕见的甲状腺恶性肿瘤，起源于滤泡上皮，表现形式多样，可伴有甲状腺毒症特征或无任何相关症状。
作者报告一例49岁女性病例，该患者患有慢性阻塞性肺疾病和高血压，因前颈部肿胀4个月前来我院就诊，肿胀随时间逐渐加重。通过体格检查、实验室检查、各种影像学检查和细胞学研究，诊断为许特莱细胞肿瘤。由于诊断及时，患者入院并接受了手术，包括右侧甲状腺叶切除术。尽管这是一种罕见的甲状腺恶性肿瘤，但早期诊断和恰当治疗显示出了很好的预后。
许特莱细胞癌最初表现为甲状腺内单个、无痛的可触及肿块，晚期病例可出现压迫症状，包括吞咽困难、呼吸困难和声音嘶哑。疼痛、快速生长或明显的压迫症状提示为侵袭性肿瘤。
本病例突出了该疾病的罕见性、临床表现及治疗方式的可用性。
