Baba Hiwa O, Qaradakhy Aras J, Abdullah Ari M, Saliha Abdulwahid M, Salih Rawezh Q, Hussein H Muhammed, Ali Rawa M, Kakamad Fahmi H
Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, Iraq.
Kscien Organization, Hamdi Str, Azadi Mall, Sulaimani, Kurdistan, Iraq.
Ann Med Surg (Lond). 2021 Aug 24;69:102750. doi: 10.1016/j.amsu.2021.102750. eCollection 2021 Sep.
Hurthle cell carcinoma (HCC) is a rare type of thyroid cancer while Hodgkin's lymphoma (HL) is an uncommon cancer of the lymphocytes. The synchronous occurrence of HCC and HL in a single person has not been described in the literature. This report aims to present the first case of synchronous HCC and HL.
A 31-year-old male presented with a right side neck swelling for three months. Laboratory findings revealed elevated thyroglobulin (286.7 ng/ml). Ultrasound (US) examination showed several enlarged lymph nodes (<20mm) in the right side of the neck with increased vascularity. There was also a solitary solid thyroid nodule (23*20mm) in the right lobe. Fine needle aspiration cytology (FNAC) of the right lobe revealed Hurthle cell neoplasm, and right cervical lymph node was suspicious for Hodgkin's lymphoma. Right lobectomy with right lateral cervical excisional biopsy was performed. Histopathology confirmed HCC and HL.
HCC is a differentiated cancer occurring in old age population. Multiple factors increase the risk of HCC, including the excess iodine, history of thyroid diseases, and exposure to radiation. HL is a cancer of the lymphatic system that affects young adults and older population. There is a significant association between excess body weight and cigarette smoking with the risk of HL.
Although extremely rare, occurrence of a few cases of other thyroid carcinomas and HL could occur. However, no relation has been described between the two cancers.
许特尔细胞癌（HCC）是一种罕见的甲状腺癌，而霍奇金淋巴瘤（HL）是一种不常见的淋巴细胞癌。文献中尚未描述过同一人同时发生HCC和HL的情况。本报告旨在呈现首例同时发生HCC和HL的病例。
一名31岁男性因右侧颈部肿胀3个月就诊。实验室检查结果显示甲状腺球蛋白升高（286.7 ng/ml）。超声（US）检查显示右侧颈部有几个肿大的淋巴结（<20mm），血管增多。右叶还有一个孤立的实性甲状腺结节（23*20mm）。右叶细针穿刺细胞学检查（FNAC）显示许特尔细胞瘤，右侧颈部淋巴结怀疑为霍奇金淋巴瘤。进行了右叶切除术及右侧颈部切除活检。组织病理学证实为HCC和HL。
HCC是一种发生于老年人群的分化型癌症。多种因素会增加HCC的风险，包括碘摄入过量、甲状腺疾病史和辐射暴露。HL是一种影响年轻人和老年人群的淋巴系统癌症。体重超标和吸烟与HL的风险之间存在显著关联。
虽然极为罕见，但可能会出现少数其他甲状腺癌与HL同时发生的情况。然而，这两种癌症之间尚未发现关联。
