Nabdi Samira, Boujraf Said, Benzagmout Mohammed
Faculty of Medicine and Pharmacy of Fez, Sidi Mohamed Ben Abdellah University.
Clinical Neuroscience Laboratory, Faculty of Medicine, Sidi Mohamed Ben Abdellah University.
Ann Med Surg (Lond). 2023 Apr 5;85(5):1395-1402. doi: 10.1097/MS9.0000000000000406. eCollection 2023 May.
This paper aims to investigate the three areas [diet, physical activity (PA), and social relationship] and their relationship with depressive disorders in the North African population.
This is an observational cross-sectional study of 654 participants residing in the urban commune of Fez (=326) and the rural commune of Loulja (=328) in the province of Taounate. Participants were categorized into two groups: G1 without a current depressive episode and G2 with a current depressive episode. Risk factors, including locality, gender, marital status, age, parental status, employment status, tobacco use, alcohol consumption, social habits, and dietary patterns, were assessed. A multinomial probit model in Stata software was used to identify factors associated with depression occurrence in the population.
A total of 94.52% of the participants who engaged in PA did not experience a depressive episode (=0.001). Additionally, 45.39% of the participants in our series were on a processed diet and presented with a depressive disorder (=0.0001), the social contact (time spent with friends >1.5 h) remained strongly associated with reduced depressive symptoms when comparing the two groups (=0.001). The results showed that being rural, a smoker, an alcohol user, and having no spouse significantly increased depression in participants. The coefficient of age was negatively related to the probability of the occurrence of age-related depression; however, this factor was not significant in the model. Thus, having a spouse and/or children and spending time with friends on a healthy diet significantly decreased depression in our population.
The converging evidence suggests that physical exercise, a stable social relationship, a healthy diet, and the use of PA can alleviate depression symptoms, but limited understanding and few studies have attempted to characterize or identify the neural mechanisms of these effects.
Nonpharmaceutical interventions such as PA and dietary changes have proven to be effective treatments for depression, while maintaining positive social relationships can act as a protective factor, serving a prophylactic role in the prevention of depression.
本文旨在研究北非人群的三个领域[饮食、身体活动(PA)和社会关系]及其与抑郁症的关系。
这是一项对居住在陶纳特省非斯市城市社区(=326人)和卢尔贾农村社区(=328人)的654名参与者进行的观察性横断面研究。参与者被分为两组:G1组为目前无抑郁发作,G2组为目前有抑郁发作。评估了包括地区、性别、婚姻状况、年龄、父母状况、就业状况、烟草使用、酒精消费、社会习惯和饮食模式等风险因素。使用Stata软件中的多项概率模型来识别与人群中抑郁症发生相关的因素。
共有94.52%进行身体活动的参与者未经历抑郁发作(=0.001)。此外,我们系列中的45.39%的参与者食用加工食品并患有抑郁症(=0.0001),在比较两组时,社会接触(与朋友相处时间>1.5小时)仍然与抑郁症状减轻密切相关(=0.001)。结果表明,居住农村为农村居民、吸烟者、饮酒者以及无配偶者的抑郁症发生率显著增加。年龄系数与年龄相关抑郁症发生的概率呈负相关;然而,该因素在模型中不显著。因此,有配偶和/或孩子以及在健康饮食的同时与朋友共度时光可显著降低我们研究人群中的抑郁症发生率。
越来越多的证据表明,体育锻炼、稳定的社会关系、健康的饮食以及身体活动的运用可以缓解抑郁症状,但对此的理解有限,很少有研究试图描述或识别这些影响背后的神经机制。
事实证明,诸如身体活动和饮食改变等非药物干预措施对抑郁症有效,而保持积极的社会关系可作为一种保护因素,在预防抑郁症方面起到预防作用。