从 根部分离得到的新松香烷和瑞香烷二萜类化合物及其细胞毒性活性。
New abietane and tigliane diterpenoids from the roots of and their cytotoxic activities.
机构信息
College of Pharmacy, Jinan University, Guangzhou 510632, China.
Beijing Lianxin Pharmaceutical Co., Ltd, Beijing 102600, China.
出版信息
J Asian Nat Prod Res. 2023 Jun;25(6):519-527. doi: 10.1080/10286020.2023.2197224. Epub 2023 May 25.
Abstract
Three new abietane and two new tigliane diterpenoids were isolated from the roots Their structures were elucidated by spectroscopic methods and quantum chemical calculation. Compounds and exhibited the inhibitory activities against human cancer cells HeLa and HepG2, with IC ranging from 3.54 to 11.45 µM.
摘要
从根部分离得到三种新的枞烷和两种新的贝壳杉烷二萜类化合物。通过光谱方法和量子化学计算阐明了它们的结构。化合物 和 对人癌细胞 HeLa 和 HepG2 表现出抑制活性，IC 范围为 3.54 至 11.45 μM。
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