来自……的细胞毒性大戟烷二萜类化合物
Cytotoxic tigliane diterpenoids from .
作者信息
Chen Shuangcheng, Tsang Nga Yi, Jiang Haowen, Zhang Hongjie, Ge Xiang, Wu Yanni, Shen Yu, Xie Wenxia, Li Jinlong
机构信息
School of Pharmacy, Nantong University, Nantong, People's Republic of China.
School of Chinese Medicine, Hong Kong Baptist Universityw, Kowloon, People's Republic of China.
出版信息
Nat Prod Res. 2022 Jun;36(11):2753-2757. doi: 10.1080/14786419.2021.1924712. Epub 2021 May 7.
Two new tigliane diterpenes, named eupneonoids A () and B (), together with four known analogues () were isolated from the whole plant of Bruyns. Their structures were deduced based on the detailed spectroscopic analysis. All the isolates displayed cytotoxic effects against A549 human tumor cell lines with IC values ranging from 1.318 to 7.042 μM.
从布鲁因斯（Bruyns）全株中分离出两种新的大戟烷二萜，命名为优尼奥类化合物A（）和B（），以及四种已知类似物（）。基于详细的光谱分析推断出它们的结构。所有分离物对A549人肿瘤细胞系均显示出细胞毒性作用，IC值范围为1.318至7.042μM。
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