Hidaka A, Komatani M, Shimazu T, Sakamoto H, Suzuki Y, Kitanaka T, Sugawa T
Nihon Sanka Fujinka Gakkai Zasshi. 1986 May;38(5):778-84.
In an experiment using 103 late pregnant rabbits, the resting uterine tonus was increased by inserting a balloon into the amniotic cavity on the cervical side (n = 71) or the ovarian side (n = 52) and the effects of this increase on the maternal blood pressure, renal cortical blood flow (measured by a thermocouple method), renal arterial and carotid arterial blood flow (measured with an electromagnetic flowmeter) were studied. The findings are briefly described, as follows: The maternal blood pressure was slightly increased on both sides (by 12.0 +/- 3.5% on the cervical and by 12.0 +/- 3.8% on the ovarian side). However, there was a hemodynamic difference between the renal cortical and renal arterial blood flow on the cervical side and those on the ovarian side: They were slightly increased on the cervical side and slightly decreased on the ovarian side. On the basis of these findings, the following may be proposed: An increase in resting uterine tonus causes a rise in maternal blood pressure associated with blood redistribution from the uteroplacental vascular bed. However, the fact that the renal blood flow was decreased consequently upon the increase in resting uterine tonus raised a possibility of neurotransmission via the ovarian plexus as well as utero-renal reflex.
在一项使用103只妊娠晚期兔子的实验中，通过在宫颈侧（n = 71）或卵巢侧（n = 52）的羊膜腔内插入球囊来增加静息子宫张力，并研究这种增加对母体血压、肾皮质血流量（通过热电偶法测量）、肾动脉和颈动脉血流量（用电磁流量计测量）的影响。研究结果简要描述如下：两侧母体血压均略有升高（宫颈侧升高12.0±3.5%，卵巢侧升高12.0±3.8%）。然而，宫颈侧和卵巢侧的肾皮质血流量与肾动脉血流量之间存在血流动力学差异：宫颈侧略有增加，卵巢侧略有减少。基于这些发现，可能提出以下观点：静息子宫张力增加导致母体血压升高，同时伴有来自子宫胎盘血管床的血液重新分布。然而，静息子宫张力增加后肾血流量随之减少这一事实，增加了通过卵巢丛以及子宫-肾反射进行神经传递的可能性。
