Jessen Frank, Bohr Lara, Kruse Christopher, Dodel Richard
Klinik für Psychiatrie und Psychotherapie, Medizinische Fakultät, Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Deutschland.
Nervenarzt. 2023 Jul;94(7):609-613. doi: 10.1007/s00115-023-01492-6. Epub 2023 May 26.
Due to the demographic development, the number of dementia patients in Germany is continuously increasing. The complex care situation of those affected calls for meaningful guidelines. In 2008, the first S3 guideline on dementia was published, coordinated by the German Association for Psychiatry, Psychotherapy and Psychosomatics (DGPPN) and the German Association for Neurology (DGN) and accompanied by the Association of the Scientific Medical Societies in Germany (AWMF). An update was published in 2016. In recent years, the diagnostic possibilities for Alzheimer's disease, in particular, have greatly developed and a new disease concept has emerged that includes mild cognitive impairment (MCI) as part of the clinical manifestation of the disease and also enables the diagnosis of Alzheimer's disease in this phase. In the area of treatment, the first causal disease-modifying therapies will likely soon be available. Furthermore, epidemiological studies have also shown that up to 40% of the risks for dementia are dependent on modifiable risk factors, making prevention increasingly more important. In order to do justice to these developments a completely updated S3 guideline on dementia is currently being developed, which will be available digitally for the first time in the form of an app and which, in the sense of living guidelines, will enable rapid adjustments to progress in the future.
由于人口结构的发展,德国痴呆症患者的数量在持续增加。这些患者复杂的护理状况需要有意义的指导方针。2008年,由德国精神病学、心理治疗与身心医学协会(DGPPN)和德国神经病学协会(DGN)协调,并在德国科学医学协会联合会(AWMF)的支持下,发布了首份关于痴呆症的S3指南。2016年该指南进行了更新。近年来,尤其是阿尔茨海默病的诊断方法有了很大发展,出现了一种新的疾病概念,将轻度认知障碍(MCI)纳入该疾病临床表现的一部分,并且能够在这一阶段诊断出阿尔茨海默病。在治疗领域,首批具有病因性疾病修饰作用的疗法可能很快就会出现。此外,流行病学研究还表明,高达40%的痴呆症风险取决于可改变的风险因素,这使得预防变得越来越重要。为了适应这些发展,目前正在制定一份全面更新的痴呆症S3指南,该指南将首次以应用程序的形式以数字方式提供,并且从动态指南的意义上来说,将能够根据未来的进展迅速进行调整。