School of Nutrition, Food Science and Technology, College of Agriculture, Hawassa University, Hawassa P.O. Box 05, Ethiopia.
Hawassa College of Teacher Education, Hawassa, Ethiopia.
Toxins (Basel). 2023 Apr 24;15(5):307. doi: 10.3390/toxins15050307.
The uses of natural plant origin bioactive compounds are emerging as a promising strategy to detoxify aflatoxin B1 (AFB1). This study aimed to explore the potential of cooking, phytochemicals content, and antioxidant activities derived from garlic, ginger, cardamom, and black cumin to detoxify AFB1 on spice mix red pepper powder () and sauté. The effectiveness of the samples was analyzed for AFB1 detoxification potential through standard methods for the examination of food and food additives. These major spices showed an AFB1 level below the detection limit. After cooking in hot water for 7 min at 85 ℃, the experimental and commercial spice mix red pepper showed the maximum AFB1 detoxification (62.13% and 65.95%, respectively). Thus, mixing major spices to produce a spice mix red pepper powder had a positive effect on AFB1 detoxification in raw and cooked spice mix red pepper samples. Total phenolic content, total flavonoid content, 2,2-diphenyl-1-picrylhydrazyl, ferric ion reducing antioxidant power, and ferrous ion chelating activity revealed good positive correlation with AFB1 detoxification at < 0.05. The findings of this study could contribute to mitigation plans of AFB1 in spice-processing enterprises. Further study is required on the mechanism of AFB1 detoxification and safety of the detoxified products.
天然植物源生物活性化合物的应用正成为一种有前途的策略，可以解毒黄曲霉毒素 B1（AFB1）。本研究旨在探索大蒜、生姜、小豆蔻和黑孜然在烹饪、植物化学物质含量和抗氧化活性方面的潜力，以脱除辣椒粉（）和炒香中的 AFB1。通过食品和食品添加剂检验标准方法，分析样品对 AFB1 解毒潜力的有效性。这些主要香料的 AFB1 含量低于检测限。在 85℃下热水中煮 7 分钟后，实验和商业混合辣椒粉显示出最大的 AFB1 解毒作用（分别为 62.13%和 65.95%）。因此，将主要香料混合生产辣椒粉对生的和熟的混合辣椒粉样品中的 AFB1 解毒有积极作用。总酚含量、总黄酮含量、2,2-二苯基-1-苦基肼、铁离子还原抗氧化能力和亚铁离子螯合活性与 AFB1 解毒呈良好正相关（<0.05）。本研究结果可为香料加工企业的 AFB1 缓解计划做出贡献。需要进一步研究 AFB1 解毒机制和解毒产品的安全性。
