Staderini Enrico M, Kambampati Harish, Ramakrishnaiah Amith K, Mugnaini Stefano, Magrini Andrea, Gentili Sandro
Healthy World Association Switzerland, 1400 Yverdon-les-Bains, Switzerland.
Doctorate School in Industrial Engineering, "Tor Vergata" University of Rome, 00133 Roma, Italy.
Bioengineering (Basel). 2023 May 4;10(5):552. doi: 10.3390/bioengineering10050552.
Heart rate variability (HRV) is commonly intended as the variation in the heart rate (HR), and it is evaluated in the time and frequency domains with various well-known methods. In the present paper, the heart rate is considered as a time domain signal, at first as an abstract model in which the HR is the instantaneous frequency of an otherwise periodic signal, such as with an electrocardiogram (ECG). In this model, the ECG is assumed to be a frequency modulated signal, or carrier signal, where HRV or HRV(t) is the time-domain signal which is frequency modulating the carrier ECG signal around its average frequency. Hence, an algorithm able to frequency demodulate the ECG signal to extract the signal HRV(t) is described, with possibly enough time resolution to analyse fast time-domain variations in the instantaneous HR. After exhaustive testing of the method on simulated frequency modulated sinusoidal signals, the new procedure is eventually applied on actual ECG tracings for preliminary nonclinical testing. The purpose of the work is to use this algorithm as a tool and a more reliable method for the assessment of heart rate before any further clinical or physiological analysis.
心率变异性(HRV)通常指心率(HR)的变化,它通过各种知名方法在时域和频域进行评估。在本文中,心率被视为时域信号,首先作为一种抽象模型,其中心率是其他周期性信号(如心电图(ECG))的瞬时频率。在该模型中,心电图被假定为调频信号或载波信号,其中HRV或HRV(t)是围绕其平均频率对载波心电图信号进行频率调制的时域信号。因此,描述了一种能够对心电图信号进行频率解调以提取信号HRV(t)的算法,该算法可能具有足够的时间分辨率来分析瞬时心率的快速时域变化。在对模拟调频正弦信号进行该方法的详尽测试之后,最终将新程序应用于实际心电图描记图进行初步非临床测试。这项工作的目的是将该算法用作一种工具和更可靠的方法,以便在进行任何进一步的临床或生理分析之前评估心率。