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通过比较意大利职业暴露致癌物登记处(SIREP)的数据与国际癌症研究机构(IARC)证据评估职业致癌风险。

Assessment of Occupational Carcinogenic Risk by Comparing Data from the Italian Register of Occupational Exposures to Carcinogens (SIREP) with the International Agency for Research on Cancer (IARC) Evidence.

机构信息

Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, National Institute for Insurance against Accident at Work (INAIL), 00143 Rome, Italy.

出版信息

Int J Environ Res Public Health. 2023 May 17;20(10):5850. doi: 10.3390/ijerph20105850.

DOI:10.3390/ijerph20105850
PMID:37239576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10218431/
Abstract

In Italy, the National Register on Occupational Exposure to Carcinogens (SIREP) is established pursuant to article 243 of Legislative Decree 81/2008 and is aimed to collect information on the exposure of workers to carcinogens transmitted by employers. The aim of this study is to assess its level of implementation comparing prevailing carcinogens reported in SIREP with the monitoring of risks in the workplace evidenced by the International Agency for Research on Cancer (IARC). The data reported in the SIREP have been integrated with IARC and the database on carcinogenic risk in the workplace named MATline in order to build a matrix containing the carcinogens classified according to the IARC (Group 1 and 2A agents) and to a semi-quantitative indicator of risk level (High or Low) calculated upon the number of exposures reported in SIREP. The matrix contains the following data: carcinogens, economic sector (NACE Rev2 coding) and cancer sites. The comparison between SIREP and IARC evidence allowed us to highlight situations with a high risk of carcinogenicity and to address appropriate actions of prevention to contain the risks of exposure to carcinogenic substances.

摘要

在意大利,国家职业致癌物登记册(SIREP)是根据 2008 年第 81 号法令第 243 条设立的,旨在收集雇主传播的工人接触致癌物的信息。本研究旨在通过比较 SIREP 中报告的流行致癌物与国际癌症研究机构(IARC)证明的工作场所风险监测,评估其实施水平。SIREP 中报告的数据与 IARC 和名为 MATline 的工作场所致癌风险数据库进行了整合,以便根据 IARC(第 1 组和 2A 组)和根据 SIREP 报告的暴露次数计算的风险水平(高或低)半定量指标,构建一个包含致癌物质的矩阵。该矩阵包含以下数据:致癌物、经济部门(NACE Rev2 编码)和癌症部位。SIREP 与 IARC 证据之间的比较使我们能够突出具有高度致癌风险的情况,并采取适当的预防措施来控制接触致癌物质的风险。

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本文引用的文献

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Asbestos Exposure and Malignant Mesothelioma in Construction Workers-Epidemiological Remarks by the Italian National Mesothelioma Registry (ReNaM).石棉暴露与建筑工人恶性间皮瘤——意大利国家间皮瘤登记处(ReNaM)的流行病学述评。
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