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维生素D水平会改变短期面部提升干预措施的效果吗?

Can Vitamin D Levels Alter the Effectiveness of Short-Term Facelift Interventions?

作者信息

Trifan Daniela Florina, Tirla Adrian Gheorghe, Moldovan Andrada Florina, Moș Calin, Bodog Florian, Maghiar Teodor Traian, Manole Felicia, Ghitea Timea Claudia

机构信息

Faculty of Medicine and Pharmacy, Doctoral School, University of Oradea, 410068 Oradea, Romania.

Faculty of Medicine and Pharmacy, Medicine Department, University of Oradea, 410068 Oradea, Romania.

出版信息

Healthcare (Basel). 2023 May 20;11(10):1490. doi: 10.3390/healthcare11101490.

Abstract

Facelifting is increasingly popular among the population. It exceeded the limits of post-traumatic facia-reconstruction. Both the demand and the methods available are getting increasingly diverse. The minimally invasive technique revolutionized the facelift, although it took some time to completely comprehend the mechanics. The roles of vitamin D in numerous physiological processes in which it is involved have mostly been elucidated in the last decade. Our hypothesis is based on one of these roles, that is, vitamin D intervenes in changing the type of collagen by changing its location; therefore, collagen will have a supporting role for the subcutaneous tissue. A group of 156 patients with different facelifting methods was followed: 93 minimally invasive (NC), 49 classical surgery (C) and 14 with the combined technique (NC + C). The change in the subcutaneous tissue was monitored by an elastograph. The level of vitamin D was monitored in order to assess the immediate and long-term effects of vitamin D on the progression of subcutaneous fibrosis. It was proven that an optimal level of vitamin D has a beneficial effect in maintaining the volume of subcutaneous tissue in patients from the NC and NC + C groups, the best results being in the NC + C group. An increase in the subcutaneous volume was recorded, which leads to a decrease in elasticity (statistical significance < 0.05) and the lowering of the subcutaneous tissue, and an increased amount of lowering corresponds to a lowering of vitamin D levels.

摘要

面部提升在人群中越来越受欢迎。它超出了创伤后面部重建的范畴。需求和可用方法都日益多样化。微创技术彻底改变了面部提升,尽管人们花了一些时间才完全理解其机制。维生素D在其涉及的众多生理过程中的作用大多是在过去十年中才得以阐明。我们的假设基于其中一个作用,即维生素D通过改变胶原蛋白的位置来干预其类型变化;因此,胶原蛋白将对皮下组织起到支撑作用。对一组采用不同面部提升方法的156名患者进行了跟踪:93例采用微创(NC),49例采用传统手术(C),14例采用联合技术(NC + C)。通过弹性成像仪监测皮下组织的变化。监测维生素D水平以评估维生素D对皮下纤维化进展的即时和长期影响。结果证明,最佳水平的维生素D对维持NC组和NC + C组患者皮下组织的体积具有有益作用,其中NC + C组效果最佳。记录到皮下体积增加,这导致弹性降低(统计学意义<0.05)以及皮下组织下移,而下移量增加与维生素D水平降低相对应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf0e/10218689/1963dd5cd9f8/healthcare-11-01490-g001.jpg

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