Onea Minz Sorina-Georgiana, Pallag Annamaria, Burlou-Nagy Fati Cristina, Jurca Tünde, Vicaș Laura Gratiela, Eleonora Marian, Olah Neli Kinga, Kiss Rita, Pașca Bianca
Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Life (Basel). 2025 Jan 8;15(1):67. doi: 10.3390/life15010067.
Medik. (CBP) is a species with antibacterial, anti-inflammatory, antioxidant, anticancer, and hepatoprotective effects. We have chosen to study this species because, although it is a common plant with a distinctive fruit appearance, its effects are not fully understood. The aim of this study was to characterize the histoanatomy of the vegetative, reproductive organs and to characterize CBP extracts in terms of bioactive compounds and its antioxidant capacity. This study investigated the quantitative chemical composition of this species using the HPLC method, revealing the total content in polyphenols, flavonoids, and anthocyanins, and investigated the antioxidant potential through fluorescence recovery after photobleaching (FRAP assay), cupric ion (Cu) reduction, (CUPRAC assay), and a free radical scavenging method (DPPH). Our results show that CBP is a rich source of flavonoids, mainly from the extract obtained from the fruits; it has an antioxidant capacity, with the highest values being obtained from mature flowers and ripe fruits. Of the active principles, the highest amounts, according to HPLC determinations, were obtained in flowers and are represented by hyperoside. Thus, we can recommend the studied species for phytopharmaceutical preparations.
Medik.(CBP)是一种具有抗菌、抗炎、抗氧化、抗癌和保肝作用的物种。我们之所以选择研究这个物种,是因为尽管它是一种果实外观独特的常见植物,但其作用尚未完全了解。本研究的目的是对营养器官和生殖器官进行组织解剖学特征分析,并从生物活性化合物及其抗氧化能力方面对CBP提取物进行特征分析。本研究采用高效液相色谱法研究了该物种的定量化学成分,揭示了多酚、黄酮类化合物和花青素的总含量,并通过光漂白后荧光恢复(FRAP法)、铜离子(Cu)还原(CUPRAC法)和自由基清除法(DPPH)研究了其抗氧化潜力。我们的结果表明,CBP是黄酮类化合物的丰富来源,主要来自果实提取物;它具有抗氧化能力,成熟花和成熟果实的抗氧化能力值最高。根据高效液相色谱测定,活性成分含量最高的是花,以金丝桃苷为代表。因此,我们可以推荐所研究的物种用于植物药物制剂。