Tzelves Lazaros, Somani Bhaskar, Berdempes Marinos, Markopoulos Titos, Skolarikos Andreas
2nd Department of Urology, National and Kapodistrian University of Athens, Sismanogleio Hospital, Athens, Greece.
Turk J Urol. 2021 May;47(3):183-192. doi: 10.5152/tud.2021.21030.
Laser disintegration of urinary stones is a cornerstone of urolithiasis treatment in the modern era. Despite the wide clinical use of stone lasers, basic and advanced technological achievements and developments are difficult to comprehend and interpret by the average urologist. A descriptive analysis of laser production and stone disintegration mechanisms was performed. We focused on physics of modern types of lithotripters, the construction of laser fibers, laser parameters, new modes, settings, and lithotripsy techniques. The main principle of laser emission remains the same since the first emitting laser was produced. Peak power density and short interaction time lead to photothermal effects responsible for stone disintegration. Modern lithotripters such as Holmium: YAG (low/high power, Moses technology) and thulium fiber laser show basic construction differences with the physical properties of the latter being superior, at least in in vitro studies. By adjusting lasing parameters, a wide spectrum of stone ablation from fragmentation to dusting can be achieved. New technology allows for the production of real dust. Knowledge of laser fiber construction and physical properties are useful in marketing and clinical use. Urologists should understand the physical and physiological background of the lasers used in their everyday practice for stone fragmentation.
激光碎石术是现代尿路结石治疗的基石。尽管结石激光在临床上广泛应用,但普通泌尿外科医生难以理解和解读其基础及先进的技术成果与进展。本文对激光产生及结石破碎机制进行了描述性分析。我们聚焦于现代碎石机的物理原理、激光光纤的构造、激光参数、新模式、设置及碎石技术。自第一台发射激光诞生以来,激光发射的主要原理保持不变。峰值功率密度和短相互作用时间会导致产生负责结石破碎的光热效应。现代碎石机,如钬激光(低/高功率,摩西技术)和掺铥光纤激光,在基础构造上存在差异,至少在体外研究中,后者的物理特性更优越。通过调整激光参数,可实现从结石破碎到粉末化的广泛结石消融范围。新技术能够产生真正的粉末。了解激光光纤的构造和物理特性对市场营销及临床应用很有帮助。泌尿外科医生应了解日常用于结石破碎的激光的物理和生理背景。