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一项为期 1 年的标准化防晒对比传统日常护肤方案对皮肤 II-VI 型人群面部皮肤老化征象影响的前瞻性随机试验。

Impact on facial skin aging signs of a 1-year standardized photoprotection over a classical skin care routine in skin phototypes II-VI individuals: A prospective randomized trial.

机构信息

L'Oréal Research and Innovation, Clichy, France.

L'Oréal Research and Innovation, Rio de Janeiro, Brazil.

出版信息

J Eur Acad Dermatol Venereol. 2023 Oct;37(10):2090-2097. doi: 10.1111/jdv.19230. Epub 2023 Jun 9.

Abstract

BACKGROUND

Data reflecting the impact of photoprotection on cutaneous aging are scarce and mostly limited to fair skin.

OBJECTIVE

To assess the effectiveness of a photoprotective product in counteracting the photoaging process in different skin phototypes over 1 year compared against a classical routine.

MATERIALS AND METHODS

Two hundred and ninety Brazilian women aged 30-65 years, with skin phototype II-VI were equally randomized in two groups. Group 1 kept on their routine whereas Group 2 applied, twice daily, a photoprotective product (SPF 60, PPD = 24.1) replacing the one they routinely used. Volunteers reported the duration of their daily sun-exposure. Standardized photographs taken at D and D were analysed by 15 dermatologists to assess eight wrinkles and pigmentation signs.

RESULTS

A global increase in severity was reported which was significant for Group 1. This increase was lower in Group 2 where only half the signs showed significant worsening. In Group 2 versus Group 1, the increase in forehead wrinkles, marionette lines, wrinkles created by ptosis and size of dark spot was significantly (p < 0.05) decreased by 30%-50%.

CONCLUSION

Daily application of a high photoprotective product significantly decreases the progression of skin aging signs after 1 year in skin phototypes II-VI.

摘要

背景

反映光防护对皮肤衰老影响的数据稀缺,且大多仅限于白皙皮肤。

目的

评估与传统常规相比,在 1 年时间内,一种光防护产品在不同皮肤类型中对光老化过程的影响。

材料与方法

290 名年龄在 30-65 岁之间、皮肤类型为 II-VI 的巴西女性被平均分为两组。第 1 组继续使用常规护肤产品,第 2 组每天使用两次光防护产品(SPF60,PPD=24.1)代替其常规使用的产品。志愿者报告他们每天的日照时间。在 D 和 D 时拍摄的标准化照片由 15 名皮肤科医生进行分析,以评估 8 个皱纹和色素沉着标志。

结果

报告称两组的严重程度都有所增加,第 1 组的增加更为显著。第 2 组的增加幅度较低,其中只有一半的迹象显示出明显恶化。与第 1 组相比,第 2 组的额部皱纹、木偶纹、下垂引起的皱纹和黑斑大小增加了 30%-50%。

结论

在皮肤类型 II-VI 中,每天使用高防晒产品可显著减缓皮肤老化迹象在 1 年后的进展。

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