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多功能自动荧光纳米凝胶用于治疗诊断。

Multi-functional auto-fluorescent nanogels for theranostics.

机构信息

Department of Immunology and Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.

Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.

出版信息

J Neurovirol. 2023 Jun;29(3):252-257. doi: 10.1007/s13365-023-01138-y. Epub 2023 May 29.

DOI:10.1007/s13365-023-01138-y
PMID:37248372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10404193/
Abstract

Here in the present article, the state of art for nanotechnology-enabled nanogel theranostics and the upcoming concepts in nanogel-based therapeutics are summarized. The benefits, innovation, and prospects of nanogel technology are also briefly presented.

摘要

本文总结了纳米技术使能的纳米凝胶治疗学的最新进展和基于纳米凝胶的治疗学的新兴概念。本文还简要介绍了纳米凝胶技术的优势、创新和前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3404/10404193/0453ea729bb1/13365_2023_1138_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3404/10404193/b8c7c77c652b/13365_2023_1138_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3404/10404193/d9b5d9b05aa7/13365_2023_1138_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3404/10404193/0453ea729bb1/13365_2023_1138_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3404/10404193/b8c7c77c652b/13365_2023_1138_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3404/10404193/d9b5d9b05aa7/13365_2023_1138_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3404/10404193/0453ea729bb1/13365_2023_1138_Fig3_HTML.jpg

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Overcoming the cellular barriers and beyond: Recent progress on cell penetrating peptide modified nanomedicine in combating physiological and pathological barriers.突破细胞屏障及其他:细胞穿透肽修饰纳米药物在对抗生理和病理屏障方面的最新进展。
Asian J Pharm Sci. 2022 Jul;17(4):523-543. doi: 10.1016/j.ajps.2022.05.002. Epub 2022 Jun 23.
3
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Recent Advances in Nanotherapeutics for Neurological Disorders.神经疾病的纳米治疗新进展
ACS Appl Bio Mater. 2023 Jul 17;6(7):2614-2621. doi: 10.1021/acsabm.3c00254. Epub 2023 Jun 27.
Neurospecific fabrication and toxicity assessment of a PNIPAM nanogel encapsulated with -tephrostachin for blood-brain-barrier permeability in zebrafish model.
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