Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA; Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.
Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA; Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.
Mol Aspects Med. 2022 Feb;83:101046. doi: 10.1016/j.mam.2021.101046. Epub 2021 Nov 4.
Magneto-electric (ME) materials with core-shell architecture where the core is made of magnetic materials have emerged as an attractive nanomaterial due to the coupling of magnetic and electric properties in the same material and the fact that both fields can be controlled which allows an on-demand, transport and release of loaded cargo. Over the last decade, biomedical engineers and researchers from various interdisciplinary fields have successfully demonstrated promising properties ranging from therapeutic delivery to sensing, and neuromodulation using ME materials. In this review, we systematically summarize developments in various biomedical fields using the nanoforms of these materials. Herein, we also highlight various promising biomedical applications where the ME nanocarriers are encapsulated in other materials such as gels and liposomes and their potential for promising therapeutics and diagnostic applications.
具有核壳结构的磁电 (ME) 材料，其中核由磁性材料制成，由于同一材料中磁性能和电性能的耦合以及可以控制两个场，从而允许按需运输和释放负载货物，因此成为一种有吸引力的纳米材料。在过去的十年中，生物医学工程师和来自不同跨学科领域的研究人员成功地展示了使用 ME 材料的从治疗药物输送到传感和神经调节的有前途的性能。在这篇综述中，我们系统地总结了使用这些材料的纳米形式在各个生物医学领域的发展。在此，我们还重点介绍了 ME 纳米载体被封装在其他材料（如凝胶和脂质体）中的各种有前途的生物医学应用，及其在有前途的治疗和诊断应用中的潜力。
