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基于罗马Ⅳ诊断标准的中国大学生功能性消化不良和肠易激综合征患病率调查

[Prevalence Survey of Functional Dyspepsia and Irritable Bowel Syndrome in Chinese College Students Based on Rome Ⅳ Diagnostic Criteria].

作者信息

Gao Xu, Liu Na, Hao Yu-Jie, Zhang Xiao-Hui, Yang Qian, Jiang Xiao-Sa, Liu Yi-Xin, Cai Ya-Qin, Song Ping, Ji Fan-Pu, Wang Jin-Hai

机构信息

Department of Gastroenterology, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710004, China.

Department of Infection, Xi'an Central Hospital, Xi'an 710004, China.

出版信息

Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 May;54(3):574-578. doi: 10.12182/20230560208.

Abstract

OBJECTIVE

To investigate the prevalence and risk factors of functional dyspepsia (FD) and irritable bowel syndrome (IBS) among college students in China.

METHODS

An online questionnaire survey of college students aged 17-35 from across China was conducted. The online questionnaire survey was supplemented by an offline survey. A total of 2025 valid samples were included for statistical analysis. test and logistic regression were performed for statistical analysis.

RESULTS

The prevalence of FD among college students who met the Rome Ⅳ diagnostic criteria was 5.5% (112/2025), with most of them, or 66.1% (74/112), suffering from postprandial discomfort syndrome (PDS). Smoking (odds ratio [ ]=2.334, 95% confidence interval [ ]: 1.187-4.589, =0.014), depression ( =2.447, 95% : 1.421-4.214, =0.001), and insomnia ( =1.947, 95% : 1.291-2.937, =0.001) were positively correlated with the prevalence of FD. The prevalence of IBS was 1.9% (38/2025), with IBS-diarrhea dominant (IBS-D) being the most important subtype that accounted for 44.7%. Anxiety ( =3.63, 95% : 1.34-9.88, =0.012) and insomnia ( =2.35, 95% : 1.18-4.68, =0.015) were positively correlated with the prevalence of IBS.

CONCLUSION

Based on Rome Ⅳ criteria, IBS and FD are not uncommon among Chinese university students. Psychological disorders and some related lifestyle factors may be related to the development of the disease. In the future, more series of studies based on different diagnostic criteria, different regions, and multiple factors should be conducted in China.

摘要

目的

调查中国大学生中功能性消化不良(FD)和肠易激综合征(IBS)的患病率及危险因素。

方法

对全国17 - 35岁的大学生进行在线问卷调查,并辅以线下调查。共纳入2025份有效样本进行统计分析。采用 检验和逻辑回归进行统计分析。

结果

符合罗马Ⅳ诊断标准的大学生中,FD患病率为5.5%(112/2025),其中大多数,即66.1%(74/112)患有餐后不适综合征(PDS)。吸烟(比值比[ ] = 2.334,95%置信区间[ ]:1.187 - 4.589, = 0.014)、抑郁( = 2.447,95% :1.421 - 4.214, = 0.001)和失眠( = 1.947,95% :1.291 - 2.937, = 0.001)与FD患病率呈正相关。IBS患病率为1.9%(38/2025),以腹泻型肠易激综合征(IBS - D)为主,占44.7%。焦虑( = 3.63,95% :1.34 - 9.88, = 0.012)和失眠( = 2.35,95% :1.18 - 4.68, = 0.015)与IBS患病率呈正相关。

结论

基于罗马Ⅳ标准,IBS和FD在中国大学生中并不少见。心理障碍和一些相关生活方式因素可能与疾病的发生有关。未来,中国应开展更多基于不同诊断标准、不同地区和多种因素的系列研究。

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