Chen Qian, Sun Lu, Huang Jian, Huang Fan, Guo Shuang, Chai Yiqing
Qian Chen Department of Ultrasound, Tianjin Central Hospital of Gynecology Obstetric, Tianjin 300100, P.R. China.
Lu Sun Department of Gynecology, Tianjin Central Hospital of Gynecology Obstetric, Tianjin 300100, P.R. China.
Pak J Med Sci. 2023 May-Jun;39(3):747-751. doi: 10.12669/pjms.39.3.7372.
To explore the applicability of three-dimensional transvaginal ultrasonography (3D-TVS) in the evaluation of diminished ovarian reserve (DOR) and premature ovarian failure (POF).
One hundred and twenty female patients, who received 3D-TVS in our hospital from January 2020 to March 2022, were included in the study. Based on sex hormone examination, 25 cases were DOR (DOR-group), 32 cases were POF (POF-group) and 63 cases had normal ovarian function (Normal-group). The 3D-TVS quantitative examination results of the three groups of patients were analyzed and compared.
There was no significant difference between the DOR-group and POF-group regarding antral follicles count (AFC), ovarian volume (OV), vascularization index (VI), vascularization flow index (VFI) and flow index (FI) of left and right ovaries (p>0.05). Compared with the Normal-group, the 3D-TVS examination indexes of the DOR-group and POF-group were significantly lower, and the 3D-TVS examination results of the POF-group were significantly lower than those of the DOR-group (p<0.05). Using sex hormone examination as the gold standard, the diagnostic specificity of 3D-TVS for DOR was 80%, and the sensitivity and accuracy were 90% and 88% respectively; The diagnostic specificity of POF was 87.5%, the sensitivity and accuracy were 95.8% and 93.8% respectively.
3D-TVS can provide scientific guidance for the clinical diagnosis and evaluation of DOR and POF.
探讨三维经阴道超声检查（3D-TVS）在评估卵巢储备功能下降（DOR）和卵巢早衰（POF）中的适用性。
选取2020年1月至2022年3月在我院接受3D-TVS检查的120例女性患者纳入研究。根据性激素检查结果，将患者分为DOR组25例、POF组32例和卵巢功能正常组（正常组）63例。分析比较三组患者的3D-TVS定量检查结果。
DOR组和POF组在双侧卵巢的窦卵泡计数（AFC）、卵巢体积（OV）、血管化指数（VI）、血管化血流指数（VFI）和血流指数（FI）方面差异无统计学意义（p>0.05）。与正常组相比，DOR组和POF组的3D-TVS检查指标显著降低，且POF组的3D-TVS检查结果低于DOR组（p<0.05）。以性激素检查为金标准，3D-TVS对DOR的诊断特异性为80%，敏感性和准确性分别为90%和88%；对POF的诊断特异性为87.5%，敏感性和准确性分别为95.8%和93.8%。
3D-TVS可为DOR和POF的临床诊断及评估提供科学指导。
