Palo Subrata Kumar, Nayak Soumya Ranjan, Sahoo Debadutta, Nayak Swetalina, Mohapatra Ashis Kumar, Sahoo Aviram, Dash Pujarini, Pati Sanghamitra
Model Rural Health Research Unit, ICMR-RMRCBB, Cuttack, India.
ICMR-Regional Medical Research Centre, Bhubaneswar, India.
Front Med (Lausanne). 2023 May 12;10:1131900. doi: 10.3389/fmed.2023.1131900. eCollection 2023.
Chronic kidney disease (CKD) is mostly asymptomatic until reaching an advanced stage. Although conditions such as hypertension and diabetes can cause it, CKD can itself lead to secondary hypertension and cardiovascular disease (CVD). Understanding the types and prevalence of associated chronic conditions among CKD patient could help improve screening for early detection and case management.
A cross sectional study of 252 CKD patients in Cuttack, Odisha (from the last 4 years CKD data base) was telephonically carried out using a validated Multimorbidity Assessment Questionnaire for Primary Care (MAQ-PC) tool with the help of an android Open Data Kit (ODK). Univariate descriptive analysis was done to determine the socio-demographic distribution of CKD patients. A Cramer's heat map was generated for showing Cramer's coefficient value of association of each diseases.
The mean age of participants was 54.11 (±11.5) years and 83.7% were male. Among the participants, 92.9% had chronic conditions (24.2% with one, 26.2% with two and 42.5% with three or more chronic conditions). Most prevalent chronic conditions were hypertension (48.4%), peptic ulcer disease (29.4%), osteoarthritis (27.8%) and diabetes (13.1%). Hypertension and osteoarthritis were found to be most commonly associated (Cramer's V coefficient = 0.3).
Increased vulnerability to chronic conditions among CKD patients make them at higher risk for mortality and compromised quality of life. Regular screening of CKD patient for other chronic conditions (hypertension, diabetes, peptic ulcer disease, osteoarthritis and heart diseases) would help in detecting them early and undertake prompt management. The existing national program could be leveraged to achieve this.
慢性肾脏病(CKD)在进入晚期之前大多没有症状。虽然高血压和糖尿病等疾病可导致慢性肾脏病,但慢性肾脏病本身也可导致继发性高血压和心血管疾病(CVD)。了解慢性肾脏病患者中相关慢性病的类型和患病率有助于改进筛查以便早期发现和病例管理。
在奥里萨邦库塔克对252例慢性肾脏病患者(来自过去4年的慢性肾脏病数据库)进行了一项横断面研究,借助安卓开放式数据采集工具包(ODK),使用经过验证的基层医疗多重疾病评估问卷(MAQ-PC)工具通过电话进行调查。进行单变量描述性分析以确定慢性肾脏病患者的社会人口统计学分布。生成了一张克莱姆热图以显示每种疾病关联的克莱姆系数值。
参与者的平均年龄为54.11(±11.5)岁,83.7%为男性。在参与者中,92.9%患有慢性病(24.2%患有一种,26.2%患有两种,42.5%患有三种或更多慢性病)。最常见的慢性病是高血压(48.4%)、消化性溃疡病(29.4%)、骨关节炎(27.8%)和糖尿病(13.1%)。发现高血压和骨关节炎最常相关(克莱姆V系数 = 0.3)。
慢性肾脏病患者患慢性病的易感性增加,使他们面临更高的死亡风险和生活质量受损风险。定期对慢性肾脏病患者进行其他慢性病(高血压、糖尿病、消化性溃疡病、骨关节炎和心脏病)筛查将有助于早期发现并及时进行管理。可以利用现有的国家项目来实现这一点。