Sun Xiaoyu, Xu Haichun, Qu Huiling, Dong Wenwu
Department of Neurology, The General Hospital of Northern Theater Command, Shenyang, China.
Department of Psychiatry, Shenyang Jing'an Mental Health Hospital, Shenyang, China.
Front Aging Neurosci. 2023 May 11;15:1144804. doi: 10.3389/fnagi.2023.1144804. eCollection 2023.
Alzheimer's disease (AD) is a major disease that affects the elderly worldwide. Several studies have revealed that vitamins may influence the risk of developing AD. However, information in this field remains ambiguous. Therefore, this study aimed to examine the relationship between AD and vitamins, identify journal publications and collaborators, and analyze keywords and research trends using a bibliometric method.
We systematically searched the Web of Science (WOS) Core Collection for papers published on AD and vitamins. Retrieved data regarding institutions, journals, countries, authors, journal distribution, keywords, and so on. SPSS 25 software was used for the statistical analysis, and CiteSpace V.6.1.R6 was used to visualize the information through collaborative networks.
A total of 2,838 publications were ultimately included in accordance with the specified inclusion criteria. The number of publications gradually increased from 1996 to 2023, with papers published in 87 countries/regions and 329 institutions. China (centrality: 0.02) and the University of Kentucky (centrality: 0.09) were the major research countries and institutions, respectively. NEUROLOGY was cited most frequently, reaching 1,573, and had the greatest impact. The cited keywords show that "Alzheimer's disease," "oxidative stress," "vitamin E," and "dementia" have been research hotspots in recent years. Beta-carotene emerged in 2023 and was identified as a developmental trend in this field.
This is the first bibliometric analysis of vitamins associated with AD. We identified 2,838 articles in the field of vitamins and AD, analyzed the information of major countries/regions, institutions, and core journals in this field, and summarized the research hotspots and frontiers. These findings provide useful information for researchers to explore the role of vitamins in AD further.
阿尔茨海默病（AD）是一种影响全球老年人的主要疾病。多项研究表明，维生素可能会影响患AD的风险。然而，该领域的信息仍不明确。因此，本研究旨在通过文献计量学方法研究AD与维生素之间的关系，识别期刊出版物和合作者，并分析关键词和研究趋势。
我们系统地检索了科学网（WOS）核心合集，以查找关于AD和维生素的已发表论文。检索了有关机构、期刊、国家、作者、期刊分布、关键词等数据。使用SPSS 25软件进行统计分析，并使用CiteSpace V.6.1.R6通过合作网络将信息可视化。
根据指定的纳入标准，最终共纳入2838篇出版物。出版物数量从1996年到2023年逐渐增加，论文发表于87个国家/地区的329个机构。中国（中心性：0.02）和肯塔基大学（中心性：0.09）分别是主要的研究国家和机构。《神经病学》被引用次数最多，达到1573次，影响最大。被引用的关键词表明，“阿尔茨海默病”“氧化应激”“维生素E”和“痴呆症”是近年来的研究热点。β-胡萝卜素于2023年出现，并被确定为该领域的一个发展趋势。
这是首次对与AD相关的维生素进行文献计量分析。我们在维生素与AD领域识别出2838篇文章，分析了该领域主要国家/地区、机构和核心期刊的信息，并总结了研究热点和前沿。这些发现为研究人员进一步探索维生素在AD中的作用提供了有用信息。
