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在 COVID-19 大流行期间开发和验证医院人员的生物风险评估工具。

Development and validation of a biological risk assessment tool among hospital personnel under COVID-19 pandemic conditions.

机构信息

Department of Occupational Health, School of Health, Kashan University of Medical Sciences, Kashan, Iran.

Social Determinants of Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.

出版信息

PLoS One. 2023 May 30;18(5):e0286298. doi: 10.1371/journal.pone.0286298. eCollection 2023.

Abstract

The need for a biological disease risk assessment method to prevent the contagion of these diseases, particularly among healthcare personnel, is crucial. Therefore, this study aimed to develop and validate a biological risk assessment tool for biological agents among hospital personnel under COVID-19 conditions. This cross-sectional study was performed on 301 employees in two hospitals. Firstly, we identified the items affecting the contagion of biological agents. Then, we computed the weight of the items using the Fuzzy Analytical Hierarchy Process (FAHP) method. We used the identified items and the estimated weights in the next step to develop a predictive equation. The outcome of this tool was the risk score of biological disease contagion. After that, we used the developed method to evaluate the biological risk of the participants. The ROC curve was also used to reveal accuracy of developed method. In this study, 29 items were identified and categorized into five dimensions, including environmental items, ventilation items, job items, equipment-related items, and organizational items. The weights of these dimensions were estimated at 0.172, 0.196, 0.255, 0.233, and 0.144, respectively. The final weight of items was used to develop a predictive equation. The area under ROC curves (AUC) was also calculated as 0.762 (95% CI: 0.704, 0.820) (p<0.001). The tools developed using these items had acceptable diagnostic accuracy for predicting the risk of biological diseases in health care. Therefore, one can apply it in identifying persons exposed to dangerous conditions.

摘要

需要一种生物疾病风险评估方法来预防这些疾病的传播,特别是在医护人员中。因此,本研究旨在开发和验证一种针对 COVID-19 条件下医院人员的生物制剂生物风险评估工具。这是一项横断面研究,在两家医院进行,共纳入 301 名员工。首先,我们确定了影响生物制剂传播的项目。然后,我们使用模糊层次分析法(FAHP)计算项目的权重。我们在下一步中使用识别出的项目和估计的权重来开发预测方程。该工具的结果是生物疾病传播的风险评分。之后,我们使用开发的方法评估参与者的生物风险。还使用 ROC 曲线揭示开发方法的准确性。在这项研究中,确定了 29 个项目,并将其分为五个维度,包括环境项目、通风项目、工作项目、设备相关项目和组织项目。这些维度的权重估计分别为 0.172、0.196、0.255、0.233 和 0.144。最终,使用项目的综合权重来开发预测方程。ROC 曲线下的面积(AUC)也计算为 0.762(95%CI:0.704,0.820)(p<0.001)。使用这些项目开发的工具对预测医疗保健中生物疾病风险具有可接受的诊断准确性。因此,可以将其应用于识别暴露于危险条件的人员。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44c2/10228796/505a1c06e881/pone.0286298.g001.jpg

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