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剖宫产术后瘢痕部位妊娠的治疗:2018-2022 年秘鲁利马的队列研究。

Treatment of ectopic pregnancy implanted on cesarea scar: cohort study 2018-2022, Lima, Peru.

机构信息

Hospital Nacional Alberto Sabogal Sologuren - EsSalud, Lima (Perú)..

Hospital Nacional Edgardo Rebagliati Martins - EsSalud, Lima (Perú)..

出版信息

Rev Colomb Obstet Ginecol. 2023 Jun 30;74(2):15-30. doi: 10.18597/rcog.3958.

Abstract

OBJECTIVES

To describe the clinical characteristics and treatment of ectopic pregnancy arising in the cesarean section scar, as well as its complications and obstetric prognosis.

MATERIAL AND METHODS

Retrospective cohort study of pregnant women with the diagnosis of a scar pregnancy in accordance with Maternal-Fetal Medicine Society criteria, seen between January 2018 and March 2022 in two high complexity institutions of the social security system, located in Lima, Peru. Consecutive sampling was used. Baseline sociodemographic and clinical variables were measured, including diagnosis, type of treatment, complications and obstetric prognosis. A descriptive analysis was performed.

RESULTS

Out of 29,919 deliveries, 17 patients were included. Of these, 41.2 % received medical management and the rest were treated surgically. Successful management with intra-gestational sac methotrexate was performed in two patients with ectopic pregnancy type 2. Four patients required total hysterectomy. Six patients became pregnant after the treatment and 4 completed their pregnancy with healthy mother and neonate pairs.

CONCLUSIONS

Ectopic pregnancy implanted in a cesarean section scar is an infrequent occurrence for which medical and surgical management options are available with apparently good outcomes. Further studies of better methodological quality and random assignment are needed in order to help characterize the safety and effectiveness of the various therapeutic options for women with suspected scar pregnancy.

摘要

目的

描述剖宫产瘢痕部位妊娠的临床特征和治疗方法,以及其并发症和产科预后。

材料和方法

这是一项回顾性队列研究,纳入了 2018 年 1 月至 2022 年 3 月期间在秘鲁利马两家高复杂度社会保障体系机构就诊的符合母婴医学学会标准的瘢痕妊娠孕妇。采用连续抽样。测量了基线社会人口学和临床变量,包括诊断、治疗类型、并发症和产科预后。进行了描述性分析。

结果

在 29919 例分娩中,有 17 例患者被纳入研究。其中,41.2%接受了药物治疗,其余接受了手术治疗。2 例 2 型异位妊娠患者接受宫内孕囊甲氨蝶呤治疗成功。4 例患者需要行全子宫切除术。6 例患者在治疗后怀孕,4 例患者母婴健康。

结论

剖宫产瘢痕部位妊娠是一种罕见的情况,有药物和手术治疗选择,且结局似乎较好。需要进一步开展方法学质量更好的随机对照研究,以帮助明确疑似瘢痕妊娠妇女的各种治疗选择的安全性和有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e7d/10237182/e250eb66a858/2463-0225-rcog-74-02-3958-gf1.jpg

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