University Hospital of Münster, Münster, Germany.
Rosario University, Bogotá, Colombia.
Am J Trop Med Hyg. 2023 May 30;109(1):53-56. doi: 10.4269/ajtmh.22-0701. Print 2023 Jul 5.
Leprosy is a chronic infection caused by Mycobacterium leprae and Mycobacterium lepromatosis that preferentially compromises peripheral nerve, skin, and mucous membranes. Colombia achieved the goal of leprosy elimination in 1997. However, in Urabá (Colombia), there has been an increase in leprosy cases beginning in 2020. This case report shows a leprosy relapse 5 decades after the initial infection debuted as a necrotizing erythema nodosum leprosum. Therefore, long-term follow-up of patients with risk factors for relapse is emphasized, especially those treated before the standard of multidrug therapy (dapsone, clofazimine, and rifampin). This case report stresses the importance the importance of clinical follow-up and surveillance of patients with these events of interest for the public health.
麻风病是由麻风分枝杆菌和麻风分枝杆菌引起的慢性感染，主要侵犯外周神经、皮肤和黏膜。哥伦比亚于 1997 年实现了消除麻风病的目标。然而，在哥伦比亚的乌拉瓦地区，自 2020 年以来，麻风病病例有所增加。本病例报告显示，首例坏死性红斑狼疮样麻风病发病 50 年后出现麻风病复发。因此，强调了对有复发风险因素的患者进行长期随访的重要性，尤其是那些在多药治疗（氨苯砜、氯法齐明和利福平）标准之前接受治疗的患者。本病例报告强调了对这些对公共卫生有重要意义的事件的临床随访和监测的重要性。
