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立场声明:麻风病:诊断、治疗和随访。

Position statement: LEPROSY: Diagnosis, treatment and follow-up.

机构信息

Department of Dermatovenereology, Ayder Referral Hospital Mekelle University, Mekelle, Tigray, Ethiopia.

Regional Dermatology Training Centre (RDTC), Moshi, Tanzania.

出版信息

J Eur Acad Dermatol Venereol. 2019 Jul;33(7):1205-1213. doi: 10.1111/jdv.15569. Epub 2019 Apr 3.

DOI:10.1111/jdv.15569
PMID:30945360
Abstract

BACKGROUND

Leprosy or Hansen's disease is a chronic infection caused by Mycobacterium leprae (M. leprae) or Mycobacterium lepromatosis (M. lepromatosis). In Europe, most of the leprosy cases are imported. However, occasionally a case is diagnosed in one of the old endemic foci. Leprosy is often not suspected because it is no longer emphasized in the medical curricula. Attention shifted from leprosy to tuberculosis and human immunodeficiency virus infections in the late 20th century, whereby the WHO leprosy programme was toned down in the conviction that leprosy was all but eliminated. The result of unawareness is a harmful doctor's delay.

MATERIAL AND METHODS

This paper focusses on clinical diagnosis, complications and treatment based on literature and experience.

RESULTS

It mentions the value of laboratory tests in classification, follow-up and detection of relapses. It discusses the etiopathology.

CONCLUSION

This is a position statement.

摘要

背景

麻风病或汉森病是由麻风分枝杆菌(M. leprae)或麻风分枝杆菌(M. lepromatosis)引起的慢性感染。在欧洲,大多数麻风病病例都是输入性的。然而,偶尔也会在一个旧的地方病流行区诊断出一例。由于医学课程不再强调,麻风病往往不被怀疑。20 世纪后期,人们的注意力从麻风病转移到结核病和人类免疫缺陷病毒感染上,因此世界卫生组织的麻风病规划有所减少,因为人们相信麻风病几乎已经被消灭。结果是医生延误了治疗,造成了有害的后果。

材料和方法

本文根据文献和经验,重点介绍了临床诊断、并发症和治疗。

结果

它提到了实验室检查在分类、随访和复发检测中的价值。它讨论了病因病理学。

结论

这是一份立场声明。

相似文献

1
Position statement: LEPROSY: Diagnosis, treatment and follow-up.立场声明:麻风病:诊断、治疗和随访。
J Eur Acad Dermatol Venereol. 2019 Jul;33(7):1205-1213. doi: 10.1111/jdv.15569. Epub 2019 Apr 3.
2
Treatment of leprosy/Hansen's disease in the early 21st century.21 世纪初的麻风病/汉森病治疗。
Dermatol Ther. 2009 Nov-Dec;22(6):518-37. doi: 10.1111/j.1529-8019.2009.01274.x.
3
[Hansen's disease: case report and review of literature].[麻风病:病例报告及文献综述]
Rev Chilena Infectol. 2008 Feb;25(1):64-9. Epub 2008 Feb 8.
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Reversible Cause of Neuropathy and Monoclonal Gammopathy of Renal Significance.具有肾脏意义的神经病和单克隆丙种球蛋白病的可逆病因。
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[Leprosy – an old infectious disease with unsolved matters].[麻风病——一种存在未解问题的古老传染病]
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Lest we forget Hansen's disease (leprosy): an unusual presentation with an acute onset of inflammatory polyarthritis and the rheumatology experience. lest we forget 汉森病(麻风病):一种以急性发作性炎症性多关节炎为表现的不常见疾病及风湿病学诊治经验。
Int J Rheum Dis. 2009 Apr;12(1):64-9. doi: 10.1111/j.1756-185X.2009.01382.x.
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Hansen's disease presenting with penile nodules.以阴茎结节为表现的麻风病。
Eur J Dermatol. 2013 Apr 1;23(2):281-2. doi: 10.1684/ejd.2013.1926.
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Recent Advancement in the Diagnosis and Treatment of Leprosy.麻风病的诊断与治疗新进展。
Curr Top Med Chem. 2018;18(18):1550-1558. doi: 10.2174/1568026618666181025100434.
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Analysis of socioeconomic condition and bacillary index with respect to the development of Hansen's disease.分析社会经济状况和细菌指数与麻风病发展的关系。
Int J Mycobacteriol. 2023 Jul-Sep;12(3):254-260. doi: 10.4103/ijmy.ijmy_108_23.
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Leprosy in the Heartland.内地的麻风病。
S D Med. 2023 Nov;76(11):486-493.

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Development and validation of a machine learning approach for screening new leprosy cases based on the leprosy suspicion questionnaire.基于麻风病疑似问卷的机器学习方法用于筛查新麻风病病例的开发与验证
Sci Rep. 2025 Feb 26;15(1):6912. doi: 10.1038/s41598-025-91462-6.
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The effect of combining antibiotics on resistance: A systematic review and meta-analysis.联合使用抗生素对耐药性的影响:一项系统评价和荟萃分析。
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Rapid test for Mycobacterium leprae infection: a practical tool for leprosy.
麻风分枝杆菌感染快速检测:麻风病的实用工具
Infect Dis Poverty. 2024 Dec 2;13(1):88. doi: 10.1186/s40249-024-01262-9.
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Leprosy.麻风病。
Nat Rev Dis Primers. 2024 Nov 28;10(1):90. doi: 10.1038/s41572-024-00575-1.
5
High-risk spatiotemporal patterns of leprosy in the southeastern region of Yunnan province from 2010 to 2022: an analysis at the township level.2010 年至 2022 年云南省东南部地区麻风病的高危时空模式:乡镇级分析。
BMC Public Health. 2024 Oct 4;24(1):2707. doi: 10.1186/s12889-024-20182-9.
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Fever of unknown origin, blood and cerebrospinal fluid involvement: a leprosy case report.不明原因发热、血液和脑脊液受累:一例麻风病例报告。
Front Immunol. 2024 Aug 27;15:1450490. doi: 10.3389/fimmu.2024.1450490. eCollection 2024.
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qPCR detection of DNA in urine samples of leprosy patients using the gene target.使用该基因靶点对麻风病患者尿液样本中的DNA进行qPCR检测。
Front Mol Biosci. 2024 Aug 13;11:1435679. doi: 10.3389/fmolb.2024.1435679. eCollection 2024.
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Erythema Nodosum Leprosum Reaction Masquerading as Rheumatoid Arthritis.伪装成类风湿关节炎的结节性红斑麻风反应
Cureus. 2024 Mar 31;16(3):e57312. doi: 10.7759/cureus.57312. eCollection 2024 Mar.
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A comparative study on the detection of Mycobacterium leprae DNA in urine samples of leprosy patients using Rlep-PCR with other conventional samples.一项关于使用Rlep-PCR检测麻风病患者尿液样本中麻风分枝杆菌DNA与其他传统样本的比较研究。
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