Entomology and Nematology Department, Florida Medical Entomology Laboratory, Institute of Food and Agricultural Sciences, University of Florida, Vero Beach, FL 32962, USA.
Laboratório de Parasitologia Médica e Biologia de Vetores, Faculdade de Medicina, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Asa Norte, Brasília/Distrito Federal CEP 70910-900, Brazil.
J Vector Ecol. 2023 Jun;48(1):12-18. doi: 10.52707/1081-1710-48.1.12.
Vector control has been an essential strategy in Brazil to manage vector-borne diseases, and the use of insecticides plays an important role in this effort. Pyriproxyfen (PPF) has become a common insect growth regulator used to control juvenile stages of mosquitoes by disturbing their growth and development. This study assesses the susceptibility and resistance status of Brazilian populations that previously showed low resistance levels to PPF. Eggs of were collected from six cities located in the northeast states of Ceará (Quixadá, Icó, and Juazeiro do Norte), and Bahia (Itabuna, Brumado, and Serrinha). We used the Rockefeller strain as an experimental control and a strain known to be susceptible to insecticides. Inhibition of emergence rates by 50% of populations varied from 0.0098-0.046 µg/L. Mosquitoes from Icó, Serrinha, and Brumado showed low resistance levels [resistance ratio (RR) = 2.33, 4.52, and 4.83, respectively], whereas moderate levels of resistance were detected in populations from Juazeiro do Norte (RR=5.83) and Itabuna (RR=7.88). collected from the Quixadá population showed a high resistance level to pyriproxyfen (RR=11). The evolution of resistance in Brazilian populations to PPF can compromise vector control efforts. Continuous monitoring of insecticide resistance in is essential for making timely management decisions for effective vector control and management.
病媒控制一直是巴西管理病媒传播疾病的重要策略，杀虫剂的使用在这方面发挥了重要作用。吡丙醚（PPF）已成为一种常见的昆虫生长调节剂，通过干扰蚊子的生长和发育来控制其幼虫阶段。本研究评估了先前对 PPF 表现出低抗性水平的巴西种群的敏感性和抗性状况。从位于塞阿拉州（奎萨达、伊科和若泽·德诺布雷）和巴伊亚州（伊塔布纳、布鲁马迪尼奥和塞拉欣哈）的六个城市收集了 的卵。我们使用洛克菲勒株作为实验对照，以及已知对杀虫剂敏感的菌株。 种群的 50%羽化率抑制率（RR）在 0.0098-0.046 µg/L 之间变化。来自伊科、塞拉欣哈和布鲁马迪尼奥的蚊子表现出低水平的抗性（RR=2.33、4.52 和 4.83），而来自若泽·德诺布雷的种群（RR=5.83）和伊塔布纳（RR=7.88）则检测到中度水平的抗性。来自奎萨达种群的 对吡丙醚表现出高抗性（RR=11）。巴西 种群对 PPF 的抗性进化可能会影响病媒控制工作。对 进行杀虫剂抗性的持续监测对于及时做出管理决策以进行有效的病媒控制和管理至关重要。
