Department of Microbiology, Vidyasagar University, Midnapore, West Bengal, India.
Institute of Health Sciences, Presidency University (Newtown Campus), Kolkata, West Bengal, India.
Methods Mol Biol. 2023;2673:505-513. doi: 10.1007/978-1-0716-3239-0_33.
In this chapter, the steps of designing candidate vaccine molecules for allergen-specific immunotherapy (AIT) using immunoinformatics are described. The most modern approach of AIT deals with carrier-bound B cell epitope and multi-epitope vaccine molecules. The strategy for designing these molecules and the bioinformatics tools and servers used for that are discussed in detail here.
在本章中,描述了使用免疫信息学设计变应原特异性免疫治疗 (AIT) 候选疫苗分子的步骤。AIT 的最现代方法涉及载体结合的 B 细胞表位和多表位疫苗分子。这里详细讨论了设计这些分子的策略以及为此使用的生物信息学工具和服务器。