Behr Matthew P, Gammal Roseann S, Matthews Michele L, Wang Victor C
Massachusetts College of Pharmacy & Health Sciences, Department of Pharmacy Practice, Boston, MA 02115, USA.
Brigham and Women's Hospital, Pain Management Center, Boston, MA 02115, USA.
Pharmacogenomics. 2023 Jun 1. doi: 10.2217/pgs-2023-0028.
To assess knowledge, confidence and perceptions of healthcare professionals specializing in primary care and pain management at Brigham and Women's Hospital, related to clinical pharmacogenomics (PGx). A 25-question online survey was distributed to 328 Brigham and Women's Hospital clinicians for analysis. Thirty-four clinicians completed the survey. Respondents had minimal experience with PGx and limited awareness of PGx resources. Although respondents expressed belief that PGx has utility to improve medication-related patient outcomes, many lack confidence to apply PGx results to their practice. For clinical drug-gene questions relevant to primary care and/or pain management, respondents scored poorly. More clinician education is needed for appropriate utilization of PGx in clinical practice as it pertains to primary care and pain management.
为评估布莱根妇女医院从事初级保健和疼痛管理的医疗保健专业人员对临床药物基因组学（PGx）的知识、信心和看法，开展了一项研究。向328名布莱根妇女医院的临床医生发放了一份包含25个问题的在线调查问卷以供分析。34名临床医生完成了调查。受访者对PGx的经验极少，对PGx资源的了解有限。尽管受访者表示相信PGx有助于改善与药物相关的患者治疗结果，但许多人缺乏将PGx结果应用于实际工作的信心。对于与初级保健和/或疼痛管理相关的临床药物-基因问题，受访者得分较低。在临床实践中，就初级保健和疼痛管理而言，为了适当利用PGx，需要对临床医生进行更多培训。
