Student Research Committee, Larestan University of Medical Sciences, Larestan, Iran.
Imam Reza Teaching Hospital, Larestan University of Medical Sciences, Larestan, Iran.
BMC Complement Med Ther. 2023 Jun 1;23(1):176. doi: 10.1186/s12906-023-04014-8.
Evidence suggests that menopause can be associated with a variety of negative psychological changes such as depression and anxiety, and improving the mental health status of women during menopause is one of the important priorities and challenges of the health system. The aim of this study was to determine the effect of saffron (Crocus sativus L., Iridaceae) herbal tea on happiness in postmenopausal women.
In this randomized clinical trial which was conducted in 2021, 72 postmenopausal women were enrolled and divided into intervention and control groups. The randomization blocks method was used for random allocation, and the Oxford Happiness Questionnaire was utilized to measure the scores. The intervention included the use of 30 mg of dried stigmas of the saffron plant, which was boiled once (in the morning, in 300 ml of boiling water for 10-15 min) and consumed with white rock candy as one cup of saffron tea daily. To compare the trend of changes and after removing the effect of other variables, generalized estimating equation (GEE) was used.
There was no significant difference between the intervention and control groups in any of the quantitative and qualitative characteristics (p > 0.05). The results of paired samples t-test showed that the happiness mean score in the intervention group increased significantly (p < 0.001) from 42.93 ± 8.54 to 61.58 ± 8.24, while in the control group, there was no significant difference between the happiness mean score at the beginning and end of the study (p = 0.861). Also, after applying the treatment program in the intervention group, there was a significant difference between the two groups in terms of the happiness mean scores (p < 0.001).
Saffron herbal tea had a positive effect on reducing depression and increasing the happiness score; thus, it is recommended that it should be used as a complementary treatment in consultation with the treating physician.
The present study was registered with the code of IRCT20210403050818N1 (Registration date: 09/04/2021) in the Iranian Registry of Clinical Trials. It was also approved by the Ethics Committee of Larestan University of Medical Sciences (Approval ID: IR.LARUMS.REC.1399.017).
有证据表明，绝经期可能与各种负面心理变化有关，如抑郁和焦虑，改善绝经期妇女的心理健康状况是卫生系统的重要优先事项和挑战之一。本研究旨在确定藏红花（Crocus sativus L.，鸢尾科）茶对绝经后妇女幸福感的影响。
在 2021 年进行的这项随机临床试验中，纳入了 72 名绝经后妇女，并将其分为干预组和对照组。采用随机分组方法进行随机分组，使用牛津幸福感问卷测量得分。干预措施包括使用 30 毫克干燥的藏红花柱头，每天一次，在 300 毫升沸水中煮沸 10-15 分钟，并用冰糖作为一杯藏红花茶饮用。为了比较变化趋势并消除其他变量的影响，使用了广义估计方程（GEE）。
干预组和对照组在任何定量和定性特征方面均无显著差异（p>0.05）。配对样本 t 检验结果表明，干预组的幸福感平均得分显著增加（p<0.001），从 42.93±8.54 增加到 61.58±8.24，而对照组在研究开始和结束时的幸福感平均得分无显著差异（p=0.861）。此外，在干预组应用治疗方案后，两组之间的幸福感平均得分存在显著差异（p<0.001）。
藏红花茶对降低抑郁和提高幸福感评分有积极作用；因此，建议在与治疗医生协商的情况下将其用作补充治疗。
本研究在伊朗临床试验注册中心注册，注册号为 IRCT20210403050818N1（注册日期：2021 年 4 月 9 日）。它还获得了拉雷斯坦大学医学科学伦理委员会的批准（批准 ID：IR.LARUMS.REC.1399.017）。
