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人类对环境中铝的暴露——暴露承诺评估。

Exposure of man to environmental aluminium--an exposure commitment assessment.

作者信息

Jones K C, Bennett B G

出版信息

Sci Total Environ. 1986 Jun;52(1-2):65-82. doi: 10.1016/0048-9697(86)90105-1.

Abstract

Aluminium is one of the most abundant elements in the environment and is released from both natural and anthropogenic sources. Representative values of aluminium concentrations in the background environment and in man are selected from available data and a pathway analysis is performed utilising the exposure commitment method. Using a derived estimate of the body burden (60 mg), a representative value for dietary intake (20 mg day-1) and fractional absorption of 0.01, a mean retention time of A1 in the body of 300 days is obtained. This corresponds to a biological half-time of 210 days. The assessment indicates that an average dietary intake rate of 20 mg day-1 contributes 660 micrograms kg-1 of aluminium to the body, while inhalation of aluminium in air makes, in comparison, a negligible contribution to the body content.

摘要

铝是环境中含量最为丰富的元素之一,可从自然和人为来源释放出来。从现有数据中选取背景环境和人体中铝浓度的代表性数值,并采用暴露承诺法进行途径分析。利用推导得出的体内负荷估计值(60毫克)、饮食摄入量的代表性数值(每天20毫克)以及0.01的分数吸收率,得出铝在体内的平均保留时间为300天。这相当于生物半衰期为210天。评估表明,每天20毫克的平均饮食摄入量会使人体铝含量增加660微克/千克,相比之下,空气中铝的吸入对人体铝含量的贡献可忽略不计。

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