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过去一年中使用大麻频率不同的初级保健患者中大麻使用障碍的患病率。

Prevalence of Cannabis Use Disorder Among Primary Care Patients with Varying Frequency of Past-Year Cannabis Use.

作者信息

Lapham Gwen T, Bobb Jennifer F, Luce Casey, Oliver Malia M, Hamilton Leah K, Hyun Noorie, Hallgren Kevin A, Matson Theresa E

机构信息

Kaiser Permanente Washington Health Research Institute, Seattle, USA.

Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA.

出版信息

J Gen Intern Med. 2025 Apr;40(5):1039-1047. doi: 10.1007/s11606-024-09061-6. Epub 2024 Oct 24.

Abstract

BACKGROUND

Valid, single-item cannabis screens for the frequency of past-year use (SIS-C) can identify patients at risk for cannabis use disorder (CUD); however, the prevalence of CUD for patients who report varying frequencies of use in the clinical setting remains unexplored.

OBJECTIVE

Compare clinical responses about the frequency of past-year cannabis use to typical use and CUD severity reported on a confidential survey.

PARTICIPANTS

Among adult patients in an integrated health system who completed the SIS-C as part of routine care (3/28/2019-9/12/2019; n = 108,950), 5000 were selected for a confidential survey using stratified random sampling. Among 1688 respondents (34% response rate), 1589 who reported past-year cannabis use on the SIS-C were included.

MAIN MEASURES

We compared patients with varying frequency of cannabis use on the SIS-C (< monthly, monthly, weekly, daily) to survey responses on the Composite International Diagnostic Interview Substance Abuse Module for CUD (any and moderate-severe CUD) and cannabis exposure measures (typical use per-week, per-day). Adjusted multinomial (categorical) and logistic regression (binary), weighted for population estimates, estimated the prevalence of outcomes across frequencies.

KEY RESULTS

Patients were predominantly middle-aged (mean = 43.3 years [SD = 16.9]), male (51.8%), white (78.2%), non-Hispanic (94.0%), and commercially insured (68.9%). The prevalence of any and moderate-severe CUD increased with greater frequency of past-year cannabis use reported on the SIS-C (p-values < 0.001) and ranged from 12.7% (6.3-19.2%) and 0.9% (0.0-2.7%) for < monthly to 44.6% (41.4-47.7%) and 20.3% (17.8-22.9%) for daily use, respectively. Greater frequency of use on the SIS-C in the clinical setting corresponded with greater per-week and per-day use on the confidential survey.

CONCLUSIONS

Among patients who reported past-year cannabis use as part of routine screening, the prevalence of CUD and other cannabis exposure measures increased with greater frequency of cannabis use, underscoring the utility of brief cannabis screens for identifying patients at risk for CUD.

摘要

背景

用于评估过去一年使用频率的有效单项大麻筛查工具(SIS-C)可识别出有大麻使用障碍(CUD)风险的患者;然而,在临床环境中报告不同使用频率的患者中CUD的患病率仍未得到探索。

目的

比较关于过去一年大麻使用频率的临床反应与在保密调查中报告的典型使用情况和CUD严重程度。

参与者

在一个综合医疗系统中,作为常规护理一部分完成SIS-C的成年患者(2019年3月28日至2019年9月12日;n = 108,950)中,采用分层随机抽样选择5000人进行保密调查。在1688名受访者(回复率34%)中,纳入了1589名在SIS-C上报告过去一年使用过大麻的受访者。

主要测量指标

我们将SIS-C上大麻使用频率不同的患者(<每月、每月、每周、每天)与关于CUD的《综合国际诊断访谈物质滥用模块》的调查回复(任何程度和中重度CUD)以及大麻暴露测量指标(每周、每天的典型使用量)进行比较。针对总体估计值进行加权的调整多项(分类)和逻辑回归(二元)分析,估计了不同频率下结果的患病率。

关键结果

患者主要为中年(平均 = 43.3岁 [标准差 = 16.9]),男性(51.8%),白人(78.2%),非西班牙裔(94.0%),且有商业保险(68.9%)。SIS-C上报告的过去一年大麻使用频率越高,任何程度和中重度CUD的患病率越高(p值 < 0.001),<每月使用频率的患病率分别为12.7%(6.3 - 19.2%)和0.9%(0.0 - 2.7%),而每天使用频率的患病率分别为44.6%(41.4 - 47.7%)和20.3%(17.8 - 22.9%)。临床环境中SIS-C上使用频率越高,保密调查中每周和每天的使用量就越高。

结论

在作为常规筛查一部分报告过去一年使用过大麻的患者中,CUD的患病率和其他大麻暴露测量指标随着大麻使用频率的增加而升高,这突出了简短大麻筛查对于识别有CUD风险患者的实用性。

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