Kerr Nathan Mitchell, Moshegov Sophia, Lim Samantha, Simos Maria
Centre for Eye Research Australia, Melbourne, VIC, Australia.
Glaucoma Investigation and Research Unit, Royal Victorian Eye and Ear Hospital, Melbourne, VIC, Australia.
Clin Ophthalmol. 2023 May 30;17:1515-1523. doi: 10.2147/OPTH.S411561. eCollection 2023.
This study aimed to evaluate and compare visual outcomes, spectacle independence, and patient satisfaction on bilaterally implanted Vivity extended depth-of-focus (EDOF) or monofocal intraocular lenses (IOLs) after cataract surgery in patients with early glaucoma.
In this retrospective, non-randomized, interventional cohort study, patients with early glaucoma undergoing cataract surgery received bilateral implantation of either EDOF (AcrySof IQ Vivity; Alcon) or monofocal (Clareon/SN6ATx/SN60WF; Alcon) IOLs. The primary outcome was monocular uncorrected intermediate visual acuity (UIVA). The secondary outcomes were monocular uncorrected distance (UDVA) and near (UNVA) visual acuity, spectacle independence, patient satisfaction, and photic phenomena. Fifty-eight eyes from 29 patients, including 32 eyes in the EDOF group and 26 eyes in the monofocal group, were included in the study.
UIVA (0.06 ± 0.16 versus 0.39 ± 0.10 LogMAR; P < 0.001) and UNVA outcomes (0.29 ± 0.10 versus 0.55 ± 0.18 LogMAR; P < 0.001) were significantly better in the EDOF group than in the monofocal group, respectively. There was no difference in UDVA and corrected distance visual acuity outcomes between the groups (P > 0.05), but both spectacle independence and patient satisfaction scores were significantly higher in the EDOF group (P < 0.001 and P < 0.05, respectively). There was no difference in self-reported photic phenomena.
Bilaterally implanted EDOF IOLs provided excellent distance vision and better intermediate and near vision than monofocal IOLs in patients with early glaucoma. Spectacle independence and patient satisfaction were significantly higher in patients who received EDOF IOLs. Photic phenomena were rare and seldom bothersome.
本研究旨在评估并比较早期青光眼患者白内障手术后双侧植入Vivity扩展景深(EDOF)人工晶状体或单焦点人工晶状体(IOL)后的视觉效果、脱镜率和患者满意度。
在这项回顾性、非随机、干预性队列研究中,接受白内障手术的早期青光眼患者双侧植入EDOF(AcrySof IQ Vivity;爱尔康)或单焦点(Clareon/SN6ATx/SN60WF;爱尔康)人工晶状体。主要结局指标为单眼未矫正中视力(UIVA)。次要结局指标为单眼未矫正远视力(UDVA)和近视力(UNVA)、脱镜率、患者满意度及光现象。纳入了29例患者的58只眼,其中EDOF组32只眼,单焦点组26只眼。
EDOF组的UIVA(0.06±0.16对0.39±0.10 LogMAR;P<0.001)和UNVA结局(0.29±0.10对0.55±0.18 LogMAR;P<0.001)分别显著优于单焦点组。两组间UDVA和矫正远视力结局无差异(P>0.05),但EDOF组的脱镜率和患者满意度评分均显著更高(分别为P<0.001和P<0.05)。自我报告的光现象无差异。
在早期青光眼患者中,双侧植入EDOF人工晶状体比单焦点人工晶状体提供了更好的远视力以及更好的中视力和近视力。接受EDOF人工晶状体的患者脱镜率和患者满意度显著更高。光现象罕见且很少造成困扰。