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慢性粒细胞白血病视网膜病变所致的急性视力丧失通过白细胞去除术得以逆转。

Acute vision loss due to CML leukemic retinopathy reversed with leukapheresis.

作者信息

Leong Sally, Do Tiffanie, Shodiya Michael, Lee Jennifer

机构信息

Division of Hematology and Medical Oncology, Department of Medicine Harbor-UCLA Medical Center Torrance California USA.

Division of Hematology and Medical Oncology, Department of Medicine UCLA Ronald Reagan Medical Center Los Angeles California USA.

出版信息

Clin Case Rep. 2023 Jun 2;11(6):e7441. doi: 10.1002/ccr3.7441. eCollection 2023 Jun.

DOI:10.1002/ccr3.7441
PMID:37273676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10238709/
Abstract

Leukemic retinopathy is a severe complication of severe leukocytosis that results from untreated chronic myelogenous leukemia (CML). Immediate cytoreduction via leukapheresis may reverse ocular manifestations and prevent permanent vision damage. We present a case of a patient with acute unilateral vision loss found to have leukemic retinopathy in the setting of untreated CML with improvement of visual symptoms after leukapheresis and initiation of hydroxyurea.

摘要

白血病视网膜病变是未经治疗的慢性粒细胞白血病（CML）导致的严重白细胞增多症的一种严重并发症。通过白细胞去除术立即进行细胞数量减少可能会逆转眼部表现并防止永久性视力损害。我们报告一例急性单侧视力丧失的患者，该患者在未经治疗的CML背景下被发现患有白血病视网膜病变，在进行白细胞去除术并开始使用羟基脲后视觉症状有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccf/10238709/a6c6e7aa9f0a/CCR3-11-e7441-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccf/10238709/e7da2046a93a/CCR3-11-e7441-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccf/10238709/a6c6e7aa9f0a/CCR3-11-e7441-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccf/10238709/e7da2046a93a/CCR3-11-e7441-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccf/10238709/a6c6e7aa9f0a/CCR3-11-e7441-g001.jpg

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A case of leukemic retinopathy mimicking common ischemic retinopathies.一例酷似常见缺血性视网膜病变的白血病性视网膜病变病例。
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Chronic myelogenous leukemia presenting with bilateral optic disc neovascularization.以双侧视盘新生血管形成表现的慢性粒细胞白血病
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