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对噬菌体P2呈溶原性的大肠杆菌的X射线敏感性

X-ray sensitivity of Escherichia coli lysogenic for bacteriophage P2.

作者信息

Ghisotti D, Zangrossi S, Sironi G

出版信息

Mol Gen Genet. 1979 Feb 1;169(3):229-35. doi: 10.1007/BF00382268.

DOI:10.1007/BF00382268
PMID:372744
Abstract

Strains of Escherichia coli C or K lysogenic for the non-inducible phage P2 show a lower survival following X-ray irradiation as compared to nonlysogenic strains. This difference in X-ray sensitivity is not accompanied by a significant difference in X-ray induced mutability. The capacity of X-irradiated P2 lysogens to multiply any of a number of unirradiated infecting phages is severely impaired. These effects of X-ray treatment can be most simply explained as a consequence of the fact that protein and RNA syntheses are strongly inhibited in P2 lysogens after X-irradiation. All the above events specifically occurring in X-rayed P2 lysogens are dependent on the P2 gene old.

摘要

对不可诱导噬菌体P2呈溶原性的大肠杆菌C或K菌株,与非溶原性菌株相比,经X射线照射后的存活率更低。X射线敏感性的这种差异并未伴随X射线诱导的突变率出现显著差异。经X射线照射的P2溶原菌繁殖多种未照射的感染噬菌体的能力受到严重损害。X射线处理的这些效应可以最简单地解释为,X射线照射后P2溶原菌中的蛋白质和RNA合成受到强烈抑制。在经X射线照射的P2溶原菌中特异性发生的所有上述事件都依赖于P2基因old。

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本文引用的文献

1
Segregation of New Lysogenic Types during Growth of a Doubly Lysogenic Strain Derived from Escherichia Coli K12.源于大肠杆菌K12的双重溶源菌株生长过程中新溶源类型的分离
Genetics. 1954 Jul;39(4):440-52. doi: 10.1093/genetics/39.4.440.
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The Growth of T2 Virus on Ultraviolet-killed Host Cells.T2病毒在紫外线灭活宿主细胞上的生长
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Deletions in bacteriophage P2. Circularity of the genetic map and its orientation relative to the DNA denaturation map.噬菌体P2中的缺失。遗传图谱的环状结构及其相对于DNA变性图谱的方向。
大肠杆菌的多核苷酸磷酸化酶是噬菌体P4免疫建立所必需的。
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An Escherichia coli gene required for bacteriophage P2-lambda interference.噬菌体P2-λ干扰所需的大肠杆菌基因。
J Virol. 1983 Dec;48(3):616-26. doi: 10.1128/JVI.48.3.616-626.1983.
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ON THE CONTROL OF THE REPLICATION OF TEMPERATE BACTERIOPHAGES SUPERINFECTING IMMUNE HOSTS.论温和噬菌体感染免疫宿主时复制的控制
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CONVERSION OF LYSOGENIC ESCHERICHIA COLI BY NONMULTIPLYING, SUPERINFECTING BACTERIOPHAGE P2.非增殖性、超感染性噬菌体P2对溶原性大肠杆菌的转化
Virology. 1964 Apr;22:634-40. doi: 10.1016/0042-6822(64)90085-6.
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[On a thermosensitive repression system in the Escherichia coli lambda bacteriophage].[关于大肠杆菌λ噬菌体中的热敏抑制系统]
C R Hebd Seances Acad Sci. 1962 Feb 19;254:1517-9.
8
A variant of phage P2 originating in Escherichia coli, strain B.源自大肠杆菌B株的噬菌体P2变种。
Virology. 1959 Jan;7(1):112-26. doi: 10.1016/0042-6822(59)90180-1.
9
Development of bacteriophage in x-ray inactivated bacteria.噬菌体在X射线灭活细菌中的发育。
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10
Bacteriophage P2: replication of the chromosome requires a protein which acts only on the genome that coded for it.噬菌体P2:染色体的复制需要一种仅作用于编码它的基因组的蛋白质。
Virology. 1970 Oct;42(2):522-33. doi: 10.1016/0042-6822(70)90295-3.