Melén I, Friberg B, Andréasson L, Ivarsson A, Jannert M, Johansson C J
Acta Otolaryngol. 1986 May-Jun;101(5-6):494-500. doi: 10.3109/00016488609108636.
Ostial and nasal patency were measured in different body positions and after phenylpropanolamine (Ppa) treatment in 12 patients earlier treated for chronic unilateral maxillary sinusitis of varying severity. Six of the sinuses were of normal appearance on sinoscopy. Phenylpropanolamine in a single dose of 100 mg was found to increase the equivalent ostial diameter significantly in the sitting and recumbent positions. The drug also reduced the nasal airway resistance. The Ppa effect might be of benefit in patients treated for chronic maxillary sinusitis.
对12例曾因不同严重程度的慢性单侧上颌窦炎接受治疗的患者，在不同体位及苯丙醇胺（Ppa）治疗后测量了窦口及鼻腔通畅情况。鼻窦镜检查显示其中6个鼻窦外观正常。发现单剂量100mg的苯丙醇胺可显著增加坐位及卧位时的等效窦口直径。该药物还降低了鼻气道阻力。Ppa的作用可能对慢性上颌窦炎患者有益。
