Madsen J, Bülow J, Nielsen N E
Acta Physiol Scand. 1986 Jun;127(2):161-6. doi: 10.1111/j.1748-1716.1986.tb07889.x.
Subcutaneous, inguinal adipose tissue from dogs was perfused with blood in which the free fatty acid (FFA) concentration was varied corresponding to FFA/albumin molar ratios between 1 and 6. Otherwise the composition of the perfusate was kept constant. In order to stimulate lipolysis, isoprenaline and theophyllamine were added to the perfusate. A raise in arterial FFA/albumin molar ratio was without influence on lipolysis (as reflected in the release of glycerol), but reduced the FFA release indicating an increased re-esterification. At FFA/albumin ratios above 3 a marked increase in vascular resistance was seen. This increase was partly reversible within the time of a perfusion. When lipolysis is stimulated in the intact organism, the effects of increasing arterial FFA/albumin ratio on re-esterification and vascular resistance may serve as feedback mechanisms regulating FFA mobilization.
用游离脂肪酸（FFA）浓度不同、对应FFA/白蛋白摩尔比在1至6之间的血液灌注犬的皮下腹股沟脂肪组织。灌注液的其他成分保持恒定。为了刺激脂肪分解，向灌注液中加入了异丙肾上腺素和氨茶碱。动脉FFA/白蛋白摩尔比的升高对脂肪分解（以甘油释放量反映）没有影响，但减少了FFA的释放，表明再酯化增加。当FFA/白蛋白比值高于3时，可见血管阻力显著增加。这种增加在灌注期间部分是可逆的。当在完整机体中刺激脂肪分解时，动脉FFA/白蛋白比值增加对再酯化和血管阻力的影响可能作为调节FFA动员的反馈机制。
