Bülow J
Pflugers Arch. 1982 Jan;392(3):230-4. doi: 10.1007/BF00584301.
In 6 dogs concentration differences for glycerol and FFA were measured between the aorta and the external pudendal vein, a vein which mainly drains subcutaneous adipose tissue in dogs, during prolonged exercise. It was found that the a-v differences increased about 2-fold for both glycerol and FFA, however great interindividual differences were found. In 4 dogs adipose tissue blood flow, glycerol and FFA a-v differences were measured simultaneously, and the mobilizations of glycerol and FFA as well as the re-esterification of FFA were calculated. After 2 h of exercise the values were in the range of 1-7 umol/(100 g.min) for FFA and glycerol mobilizations while the FFA re-esterification was in the range of 2-14 umol/(100 g.min). It was found that the FFA/albumin ratio in adipose venous blood, on average 3.6 was at a level at which the FFA mobilization has been shown to depend on the adipose tissue blood flow in isolated fat pads. In 11 dogs subcutaneous adipose tissue blood flow rose 2-fold during exercise from about 5-10 ml/(100 g.min). It is concluded that the subcutaneous adipose tissue blood flow response to exercise is equal in man and dog, that lipolysis, FFA mobilization and FFA re-esterification are increased in subcutaneous adipose tissue during exercise, and that the increase in blood flows is of importance for the enhanced FFA mobilization during exercise.
在6只犬中，于长时间运动期间测定了主动脉与阴部外静脉（一条主要引流犬皮下脂肪组织的静脉）之间甘油和游离脂肪酸（FFA）的浓度差异。结果发现，甘油和FFA的动静脉差异均增加了约2倍，不过个体间差异很大。在4只犬中，同时测定了脂肪组织血流量、甘油和FFA的动静脉差异，并计算了甘油和FFA的动员以及FFA的再酯化。运动2小时后，FFA和甘油动员的值在1 - 7 μmol/（100 g·min）范围内，而FFA再酯化的值在2 - 14 μmol/（100 g·min）范围内。结果发现，脂肪静脉血中的FFA/白蛋白比值平均为3.6，处于已表明FFA动员取决于分离脂肪垫中脂肪组织血流量的水平。在11只犬中，皮下脂肪组织血流量在运动期间从约5 - 10 ml/（100 g·min）增加了2倍。得出的结论是，人和犬皮下脂肪组织对运动的血流反应是相同的，运动期间皮下脂肪组织中的脂肪分解、FFA动员和FFA再酯化增加，并且血流量的增加对运动期间FFA动员的增强很重要。
