Department of Neurology, the First Medical Center, Chinese PLA General Hospital, Beijing, People's Republic of China.
School of Medicine, Nankai University, Tianjin, People's Republic of China.
BMC Neurol. 2023 Jun 6;23(1):218. doi: 10.1186/s12883-023-03268-6.
Among all menstruation-associated headaches, only menstrual migraine has classification criteria in the International Classification of Headache Disorders 3rd edition (ICHD-3). Other menstruation-associated headaches are not generally described. The ICHD-3 classifies menstrual migraine according to headache type, timing(on days -2 to +3 of menstruation), frequency (whether headache occurs in at least two out of three menstrual cycles), and purity(whether headache occurs at other times of the menstrual cycle), and provides a reference for research on menstruation-associated headache. However, the role of frequency and purity in the classification of menstruation- associated headache is not clear Moreover, the potential risk factors for high-frequency and pure headaches have not been explored.
The study was a secondary analysis of an epidemiological survey on menstrual migraine among nurses. Among nurses who had a headache on days -2 to +3 of menstruation, headache frequency, purity, and type were described. High-frequency vs. low-frequency and pure vs. impure headache were compared according to headache features, demographics, occupation-related factors, menstruation-related factors, and lifestyle factors.
Of all respondents, 254(18.3%) nurses who had headaches on days -2 to +3 of menstruation were included in the study. In the 254 nurses with perimenstrual headache, the proportions of migraine, tension type headache (TTH), high-frequency headache, and pure headache were 24.4%, 26.4%, 39.0%, and 42.1%, respectively. High-frequency and impure perimenstrual headache was more severe and similar to migraine. High-frequency headache was associated with more perimenstrual extremity swelling and generalized pain. Other variables were not significantly different between the groups.
Headache except for menstrual migraine accounts for a certain proportion of menstruation-associated headache and should not be ignored in research. Headache frequency and purity are related to headache type and should be equally considered in the classification of menstruation- associated headache. Perimenstrual extremity swelling and generalized pain are potential indicators of high-frequency perimenstrual headache.
ChiCTR2200056429.
在所有与月经相关的头痛中，只有月经性偏头痛在国际头痛疾病分类第 3 版（ICHD-3）中有分类标准。其他与月经相关的头痛通常没有描述。ICHD-3 根据头痛类型、时间（月经前 2 天至月经后 3 天）、频率（头痛是否至少出现在三个月经周期中的两个周期）和纯度（头痛是否出现在月经周期的其他时间）对月经性偏头痛进行分类，为研究与月经相关的头痛提供了参考。然而，频率和纯度在与月经相关的头痛分类中的作用尚不清楚。此外，高频和纯月经性头痛的潜在危险因素尚未得到探讨。
本研究是对护士月经性偏头痛进行的一项流行病学调查的二次分析。在月经前 2 天至月经后 3 天出现头痛的护士中，描述了头痛的频率、纯度和类型。根据头痛特征、人口统计学、与职业相关的因素、与月经相关的因素和生活方式因素，比较了高频与低频头痛以及纯与不纯头痛。
在所有应答者中，254 名（18.3%）在月经前 2 天至月经后 3 天出现头痛的护士被纳入研究。在 254 名患有经前期头痛的护士中，偏头痛、紧张型头痛（TTH）、高频头痛和纯头痛的比例分别为 24.4%、26.4%、39.0%和 42.1%。高频和不纯的经前期头痛更严重，且与偏头痛相似。高频头痛与更多的经前期四肢肿胀和全身疼痛有关。其他变量在组间无显著差异。
除月经性偏头痛外的头痛在与月经相关的头痛中占一定比例，在研究中不应忽视。头痛频率和纯度与头痛类型有关，应在与月经相关的头痛分类中同等考虑。经前期四肢肿胀和全身疼痛可能是高频经前期头痛的潜在指标。
ChiCTR2200056429。
